The cyclophilin inhibitor NIM-811 increases muscle cell survival with hypoxia in vitro and improves gait performance following ischemia–reperfusion in vivo

Acute ischemia–reperfusion injury in skeletal muscle is a significant clinical concern in the trauma setting. The mitochondrial permeability transition inhibitor NIM-811 has previously been shown to reduce ischemic injury in the liver and kidney. The effects of this treatment on skeletal muscle are,...

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Detalles Bibliográficos
Autores principales: El Baradie, Khairat Bahgat Youssef, Khan, Mohammad B., Mendhe, Bharati, Waller, Jennifer, O’Brien, Frederick, Hamrick, Mark W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7969970/
https://www.ncbi.nlm.nih.gov/pubmed/33731782
http://dx.doi.org/10.1038/s41598-021-85753-x

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