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Exosomes Derived From Macrophages Enhance Aerobic Glycolysis and Chemoresistance in Lung Cancer by Stabilizing c-Myc via the Inhibition of NEDD4L

As one of the most common and lethal cancer, lung cancer severely threatens the health of human. It has been reported that tumor-associated macrophages promote initiation, progression, as well as chemoresistance in human cancers. However, the underneath molecular mechanism that drives chemoresistanc...

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Detalles Bibliográficos
Autores principales: Wang, Huan, Wang, Lie, Pan, Haiyan, Wang, Yaona, Shi, Miao, Yu, Hang, Wang, Chaoye, Pan, Xinfu, Chen, Zhijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7969980/
https://www.ncbi.nlm.nih.gov/pubmed/33748098
http://dx.doi.org/10.3389/fcell.2020.620603