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Identification of novel myelin repair drugs by modulation of oligodendroglial differentiation competence

BACKGROUND: In multiple sclerosis loss of myelin and oligodendrocytes impairs saltatory signal transduction and leads to neuronal loss and functional deficits. Limited capacity of oligodendroglial precursor cells to differentiate into mature cells is the main reason for inefficient myelin repair in...

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Detalles Bibliográficos
Autores principales:	Manousi, Anastasia, Göttle, Peter, Reiche, Laura, Cui, Qiao-Ling, Healy, Luke M., Akkermann, Rainer, Gruchot, Joel, Schira-Heinen, Jessica, Antel, Jack P., Hartung, Hans-Peter, Küry, Patrick
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7970057/ https://www.ncbi.nlm.nih.gov/pubmed/33714029 http://dx.doi.org/10.1016/j.ebiom.2021.103276

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