Cargando…

Roles of the Dynamic Tumor Immune Microenvironment in the Individualized Treatment of Advanced Clear Cell Renal Cell Carcinoma

Immune checkpoint inhibitors (ICIs) are currently a first-line treatment option for clear cell renal cell carcinoma (ccRCC). However, recent clinical studies have shown that a large number of patients do not respond to ICIs. Moreover, only a few patients achieve a stable and durable response even wi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lin, Enyu, Liu, Xuechao, Liu, Yanjun, Zhang, Zedan, Xie, Lu, Tian, Kaiwen, Liu, Jiumin, Yu, Yuming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7970116/ https://www.ncbi.nlm.nih.gov/pubmed/33746989 http://dx.doi.org/10.3389/fimmu.2021.653358

Ejemplares similares

Integrative Analysis of the Genomic and Immune Microenvironment Characteristics Associated With Clear Cell Renal Cell Carcinoma Progression: Implications for Prognosis and Immunotherapy
por: Lin, Enyu, et al.
Publicado: (2022)

A Novel Immune-Related lncRNA-Based Model for Survival Prediction in Clear Cell Renal Cell Carcinoma
por: Zhang, Zedan, et al.
Publicado: (2021)

Construction of a novel gene-based model for prognosis prediction of clear cell renal cell carcinoma
por: Zhang, Zedan, et al.
Publicado: (2020)

Identifying 4 Novel lncRNAs as Potential Biomarkers for Acute Rejection and Graft Loss of Renal Allograft
por: Zhang, Zedan, et al.
Publicado: (2020)

Decoding the Immune Microenvironment of Clear Cell Renal Cell Carcinoma by Single-Cell Profiling to Aid Immunotherapy
por: Liu, Jie, et al.
Publicado: (2022)

Identification of pyroptosis-related subtypes and comprehensive analysis of characteristics of the tumor microenvironment infiltration in clear cell renal cell carcinoma
por: Zeng, Jiayi, et al.
Publicado: (2023)

Human CD8(+)CD28(−) T Suppressor Cells Expanded by IL-15 In Vitro Suppress in an Allospecific and Programmed Cell Death Protein 1-Dependent Manner
por: Feng, Fu, et al.
Publicado: (2018)

Cuproptosis-related gene FDX1 expression correlates with the prognosis and tumor immune microenvironment in clear cell renal cell carcinoma
por: Wang, Tao, et al.
Publicado: (2022)

Construction and validation of programmed cell death-based molecular clusters for prognostic and therapeutic significance of clear cell renal cell carcinoma
por: Tang, Yanlin, et al.
Publicado: (2023)

Crosstalk of necroptosis and pyroptosis defines tumor microenvironment characterization and predicts prognosis in clear cell renal carcinoma
por: Fu, Liangmin, et al.
Publicado: (2022)

Integrated single-cell and bulk characterization of cuproptosis key regulator PDHB and association with tumor microenvironment infiltration in clear cell renal cell carcinoma
por: Wu, Jiajin, et al.
Publicado: (2023)

Comprehensive analysis of cellular senescence-related genes in the prognosis, tumor microenvironment, and immunotherapy/chemotherapy of clear cell renal cell carcinoma
por: Lu, Caibao, et al.
Publicado: (2022)

Cuproptosis-related modification patterns depict the tumor microenvironment, precision immunotherapy, and prognosis of kidney renal clear cell carcinoma
por: Cai, Zhiyong, et al.
Publicado: (2022)

The ceRNA Network Has Potential Prognostic Value in Clear Cell Renal Cell Carcinoma: A Study Based on TCGA Database
por: Liu, Haosheng, et al.
Publicado: (2020)

Identification of Ligand-Receptor Pairs Associated With Tumour Characteristics in Clear Cell Renal Cell Carcinoma
por: Liu, Fahui, et al.
Publicado: (2022)

Identification of a basement membrane-based risk scoring system for prognosis prediction and individualized therapy in clear cell renal cell carcinoma
por: Tang, Yanlin, et al.
Publicado: (2023)

Metabolic Understanding of the Genetic Dysregulation in the Tumor Microenvironment of Kidney Renal Clear Cell Carcinoma
por: Xie, Junwei, et al.
Publicado: (2022)

Construction of a Lactate-Related Prognostic Signature for Predicting Prognosis, Tumor Microenvironment, and Immune Response in Kidney Renal Clear Cell Carcinoma
por: Sun, Zhuolun, et al.
Publicado: (2022)

Identification and Verification of m(7)G Modification Patterns and Characterization of Tumor Microenvironment Infiltration via Multi-Omics Analysis in Clear Cell Renal Cell Carcinoma
por: Dong, Kai, et al.
Publicado: (2022)

CGN Correlates With the Prognosis and Tumor Immune Microenvironment in Clear Cell Renal Cell Carcinoma
por: Tian, Zijian, et al.
Publicado: (2022)

A comprehensive investigation discovered the novel methyltransferase METTL24 as one presumably prognostic gene for kidney renal clear cell carcinoma potentially modulating tumor immune microenvironment
por: Jiang, Zhongji, et al.
Publicado: (2022)

Establishment and validation of a novel anoikis-related prognostic signature of clear cell renal cell carcinoma
por: Liu, Yankuo, et al.
Publicado: (2023)

Identification of immunogenic cell death-related signature on prognosis and immunotherapy in kidney renal clear cell carcinoma
por: Jiang, Silin, et al.
Publicado: (2023)

CD8(+) T Cell-Based Molecular Classification With Heterogeneous Immunogenomic Landscapes and Clinical Significance of Clear Cell Renal Cell Carcinoma
por: Wu, Xiangkun, et al.
Publicado: (2021)

Identification and validation of an immune-related gene prognostic signature for clear cell renal carcinoma
por: Hua, Shan, et al.
Publicado: (2022)

Wiskott-Aldrich syndrome gene as a prognostic biomarker correlated with immune infiltrates in clear cell renal cell carcinoma
por: Ding, Guixin, et al.
Publicado: (2023)

Integration analysis identifies MYBL1 as a novel immunotherapy biomarker affecting the immune microenvironment in clear cell renal cell carcinoma: Evidence based on machine learning and experiments
por: Wang, Tengda, et al.
Publicado: (2022)

Analyzing and validating the prognostic value and immune microenvironment of clear cell renal cell carcinoma
por: Ke, Jingwei, et al.
Publicado: (2022)

Case Report: Successful immune checkpoint inhibitor-based rechallenge in a patient with advanced renal clear cell cancer
por: He, Shengxiu, et al.
Publicado: (2023)

The Tumor Immune Microenvironment in Clear Cell Renal Cell Carcinoma
por: Monjaras-Avila, Cesar U., et al.
Publicado: (2023)

Comprehensive Analysis of Ferroptosis- and Immune-Related Signatures to Improve the Prognosis and Diagnosis of Kidney Renal Clear Cell Carcinoma
por: Xing, Xiao-Liang, et al.
Publicado: (2022)

Geospatial characterization of immune cell distributions and dynamics across the microenvironment in clear cell renal cell carcinoma
por: Chakiryan, Nicholas H, et al.
Publicado: (2023)

Prognostic and tumor microenvironmental feature of clear cell renal cell carcinoma revealed by m6A and lactylation modification-related genes
por: Yang, Lin, et al.
Publicado: (2023)

Integrated analysis to identify the prognostic and immunotherapeutic roles of coagulation-associated gene signature in clear cell renal cell carcinoma
por: Yin, Guicao, et al.
Publicado: (2023)

Comprehensive Analysis of Senescence Characteristics Defines a Novel Prognostic Signature to Guide Personalized Treatment for Clear Cell Renal Cell Carcinoma
por: Zhou, Peng, et al.
Publicado: (2022)

Mapping the tumor microenvironment in clear cell renal carcinoma by single-cell transcriptome analysis
por: Wang, Yuxiong, et al.
Publicado: (2023)

FECH Expression Correlates with the Prognosis and Tumor Immune Microenvironment in Clear Cell Renal Cell Carcinoma
por: Zhong, Guanghui, et al.
Publicado: (2022)

Radiotherapy induced immunogenic cell death by remodeling tumor immune microenvironment
por: Zhu, Songxin, et al.
Publicado: (2022)

Comprehensive investigation into cuproptosis in the characterization of clinical features, molecular characteristics, and immune situations of clear cell renal cell carcinoma
por: Wang, Bao, et al.
Publicado: (2022)

Integrating scRNA and bulk-RNA sequencing develops a cell senescence signature for analyzing tumor heterogeneity in clear cell renal cell carcinoma
por: Gong, Qiming, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_v1ob0p2dss2fv5ranu0aclr85h