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LIFR-α-dependent adipocyte signaling in obesity limits adipose expansion contributing to fatty liver disease
The role of chronic adipose inflammation in diet-induced obesity (DIO) and its sequelae including fatty liver disease remains unclear. Leukemia inhibitory factor (LIF) induces JAK-dependent adipocyte lipolysis and altered adipo/cytokine expression, suppressing in vivo adipose expansion in normal and...
Autores principales: | Guo, Tong, Gupta, Arun, Yu, Jinhai, Granados, Jorge Z., Gandhi, Aakash Y., Evers, Bret M., Iyengar, Puneeth, Infante, Rodney E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7970148/ https://www.ncbi.nlm.nih.gov/pubmed/33748712 http://dx.doi.org/10.1016/j.isci.2021.102227 |
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