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LIFR-α-dependent adipocyte signaling in obesity limits adipose expansion contributing to fatty liver disease

The role of chronic adipose inflammation in diet-induced obesity (DIO) and its sequelae including fatty liver disease remains unclear. Leukemia inhibitory factor (LIF) induces JAK-dependent adipocyte lipolysis and altered adipo/cytokine expression, suppressing in vivo adipose expansion in normal and...

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Detalles Bibliográficos
Autores principales: Guo, Tong, Gupta, Arun, Yu, Jinhai, Granados, Jorge Z., Gandhi, Aakash Y., Evers, Bret M., Iyengar, Puneeth, Infante, Rodney E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7970148/
https://www.ncbi.nlm.nih.gov/pubmed/33748712
http://dx.doi.org/10.1016/j.isci.2021.102227

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