TGF-β-induced DACT1 Biomolecular Condensates Repress Wnt Signaling To Promote Bone Metastasis

The complexity of intracellular signaling requires both a diversity of molecular players and the sequestration of activity to unique compartments within the cell. Recent findings on the role of liquid-liquid phase separation provide a distinct mechanism for spatial segregation of proteins to regulat...

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Detalles Bibliográficos
Autores principales: Esposito, Mark, Fang, Cao, Cook, Katelyn C., Park, Nana, Wei, Yong, Spadazzi, Chiara, Bracha, Dan, Gunaratna, Ramesh T., Laevsky, Gary, DeCoste, Christina J., Slabodkin, Hannah, Brangwynne, Clifford P., Cristea, Ileana M., Kang, Yibin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7970447/
https://www.ncbi.nlm.nih.gov/pubmed/33723425
http://dx.doi.org/10.1038/s41556-021-00641-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7970447/
https://www.ncbi.nlm.nih.gov/pubmed/33723425
http://dx.doi.org/10.1038/s41556-021-00641-w

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