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TGF-β-induced DACT1 Biomolecular Condensates Repress Wnt Signaling To Promote Bone Metastasis
The complexity of intracellular signaling requires both a diversity of molecular players and the sequestration of activity to unique compartments within the cell. Recent findings on the role of liquid-liquid phase separation provide a distinct mechanism for spatial segregation of proteins to regulat...
Autores principales: | Esposito, Mark, Fang, Cao, Cook, Katelyn C., Park, Nana, Wei, Yong, Spadazzi, Chiara, Bracha, Dan, Gunaratna, Ramesh T., Laevsky, Gary, DeCoste, Christina J., Slabodkin, Hannah, Brangwynne, Clifford P., Cristea, Ileana M., Kang, Yibin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7970447/ https://www.ncbi.nlm.nih.gov/pubmed/33723425 http://dx.doi.org/10.1038/s41556-021-00641-w |
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