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Adrenic Acid-Derived Epoxy Fatty Acids Are Naturally Occurring Lipids and Their Methyl Ester Prodrug Reduces Endoplasmic Reticulum Stress and Inflammatory Pain

[Image: see text] Adrenic acid (AdA, 22:4) is an ω-6 polyunsaturated fatty acid (PUFA), derived from arachidonic acid. Like other PUFAs, it is metabolized by cytochrome P450s to a group of epoxy fatty acids (EpFAs), epoxydocosatrienoic acids (EDTs). EpFAs are lipid mediators with various beneficial...

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Detalles Bibliográficos
Autores principales:	Singh, Nalin, Barnych, Bogdan, Wagner, Karen M., Wan, Debin, Morisseau, Christophe, Hammock, Bruce D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2021
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7970556/ https://www.ncbi.nlm.nih.gov/pubmed/33748630 http://dx.doi.org/10.1021/acsomega.1c00241

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