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A theoretical framework to improve the construct for chronic pain disorders using fibromyalgia as an example

Fibromyalgia (FM) is a frequent, complex condition of chronic musculoskeletal pain with no evidence for biological correlates. For this reason, despite many efforts from the medical community, its construct still appears ill defined. Promising candidate biomarkers are critically reviewed. A research...

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Detalles Bibliográficos
Autores principales: Kumbhare, Dinesh, Tesio, Luigi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7970670/
https://www.ncbi.nlm.nih.gov/pubmed/33796154
http://dx.doi.org/10.1177/1759720X20966490
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author Kumbhare, Dinesh
Tesio, Luigi
author_facet Kumbhare, Dinesh
Tesio, Luigi
author_sort Kumbhare, Dinesh
collection PubMed
description Fibromyalgia (FM) is a frequent, complex condition of chronic musculoskeletal pain with no evidence for biological correlates. For this reason, despite many efforts from the medical community, its construct still appears ill defined. Promising candidate biomarkers are critically reviewed. A research agenda is proposed for developing a clearer construct of FM. The ideal theoretical framework is one of overcoming the illness–disease dichotomy and considering reciprocal interactions between biology and behaviour. This approach may foster research in other fields of pain medicine and of medicine in general.
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spelling pubmed-79706702021-03-31 A theoretical framework to improve the construct for chronic pain disorders using fibromyalgia as an example Kumbhare, Dinesh Tesio, Luigi Ther Adv Musculoskelet Dis Review Fibromyalgia (FM) is a frequent, complex condition of chronic musculoskeletal pain with no evidence for biological correlates. For this reason, despite many efforts from the medical community, its construct still appears ill defined. Promising candidate biomarkers are critically reviewed. A research agenda is proposed for developing a clearer construct of FM. The ideal theoretical framework is one of overcoming the illness–disease dichotomy and considering reciprocal interactions between biology and behaviour. This approach may foster research in other fields of pain medicine and of medicine in general. SAGE Publications 2021-01-28 /pmc/articles/PMC7970670/ /pubmed/33796154 http://dx.doi.org/10.1177/1759720X20966490 Text en © The Author(s), 2021 https://creativecommons.org/licenses/by-nc/4.0/ This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Review
Kumbhare, Dinesh
Tesio, Luigi
A theoretical framework to improve the construct for chronic pain disorders using fibromyalgia as an example
title A theoretical framework to improve the construct for chronic pain disorders using fibromyalgia as an example
title_full A theoretical framework to improve the construct for chronic pain disorders using fibromyalgia as an example
title_fullStr A theoretical framework to improve the construct for chronic pain disorders using fibromyalgia as an example
title_full_unstemmed A theoretical framework to improve the construct for chronic pain disorders using fibromyalgia as an example
title_short A theoretical framework to improve the construct for chronic pain disorders using fibromyalgia as an example
title_sort theoretical framework to improve the construct for chronic pain disorders using fibromyalgia as an example
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7970670/
https://www.ncbi.nlm.nih.gov/pubmed/33796154
http://dx.doi.org/10.1177/1759720X20966490
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