In vitro and in vivo inhibition of malaria parasite infection by monoclonal antibodies against Plasmodium falciparum circumsporozoite protein (CSP)

Plasmodium falciparum malaria contributes to a significant global disease burden. Circumsporozoite protein (CSP), the most abundant sporozoite stage antigen, is a prime vaccine candidate. Inhibitory monoclonal antibodies (mAbs) against CSP map to either a short junctional sequence or the central (NP...

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Detalles Bibliográficos
Autores principales: Livingstone, Merricka C., Bitzer, Alexis A., Giri, Alish, Luo, Kun, Sankhala, Rajeshwer S., Choe, Misook, Zou, Xiaoyan, Dennison, S. Moses, Li, Yuanzhang, Washington, William, Ngauy, Viseth, Tomaras, Georgia D., Joyce, M. Gordon, Batchelor, Adrian H., Dutta, Sheetij
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7970865/
https://www.ncbi.nlm.nih.gov/pubmed/33674699
http://dx.doi.org/10.1038/s41598-021-84622-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7970865/
https://www.ncbi.nlm.nih.gov/pubmed/33674699
http://dx.doi.org/10.1038/s41598-021-84622-x

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