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In vitro and in vivo inhibition of malaria parasite infection by monoclonal antibodies against Plasmodium falciparum circumsporozoite protein (CSP)
Plasmodium falciparum malaria contributes to a significant global disease burden. Circumsporozoite protein (CSP), the most abundant sporozoite stage antigen, is a prime vaccine candidate. Inhibitory monoclonal antibodies (mAbs) against CSP map to either a short junctional sequence or the central (NP...
Autores principales: | Livingstone, Merricka C., Bitzer, Alexis A., Giri, Alish, Luo, Kun, Sankhala, Rajeshwer S., Choe, Misook, Zou, Xiaoyan, Dennison, S. Moses, Li, Yuanzhang, Washington, William, Ngauy, Viseth, Tomaras, Georgia D., Joyce, M. Gordon, Batchelor, Adrian H., Dutta, Sheetij |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7970865/ https://www.ncbi.nlm.nih.gov/pubmed/33674699 http://dx.doi.org/10.1038/s41598-021-84622-x |
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