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Predictors of retention in the prospective HIV prevention OKAPI cohort in Kinshasa

Retention is a key element in HIV prevention programs. In Sub-Saharan Africa most data on retention come from HIV clinical trials or people living with HIV attending HIV treatment and control programs. Data from observational cohorts are less frequent. Retention at 6-/12-month follow-up and its pred...

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Autores principales: Carlos, S., Burgueño, E., Ndarabu, A., Reina, G., Lopez-del Burgo, C., Osorio, A., Makonda, B., de Irala, J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7970874/
https://www.ncbi.nlm.nih.gov/pubmed/33686218
http://dx.doi.org/10.1038/s41598-021-84839-w
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author Carlos, S.
Burgueño, E.
Ndarabu, A.
Reina, G.
Lopez-del Burgo, C.
Osorio, A.
Makonda, B.
de Irala, J.
author_facet Carlos, S.
Burgueño, E.
Ndarabu, A.
Reina, G.
Lopez-del Burgo, C.
Osorio, A.
Makonda, B.
de Irala, J.
author_sort Carlos, S.
collection PubMed
description Retention is a key element in HIV prevention programs. In Sub-Saharan Africa most data on retention come from HIV clinical trials or people living with HIV attending HIV treatment and control programs. Data from observational cohorts are less frequent. Retention at 6-/12-month follow-up and its predictors were analyzed in OKAPI prospective cohort. From April 2016 to April 2018, 797 participants aged 15–59 years attending HIV Voluntary Counseling and Testing in Kinshasa were interviewed about HIV-related knowledge and behaviors at baseline and at 6- and 12-month follow-ups. Retention rates were 57% and 27% at 6- and 12-month follow up; 22% of participants attended both visits. Retention at 6-month was significantly associated with 12-month retention. Retention was associated with low economic status, being studying, daily/weekly Internet access, previous HIV tests and aiming to share HIV test with partner. Contrarily, perceiving a good health, living far from an antiretroviral center, daily/weekly alcohol consumption and perceiving frequent HIV information were inversely associated with retention. In conclusion, a high attrition was found among people attending HIV testing participating in a prospective cohort in Kinshasa. Considering the low retention rates and the predictors found in this study, more HIV cohort studies in Kinshasa need to be evaluated to identify local factors and strategies that could improve retention if needed.
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spelling pubmed-79708742021-03-19 Predictors of retention in the prospective HIV prevention OKAPI cohort in Kinshasa Carlos, S. Burgueño, E. Ndarabu, A. Reina, G. Lopez-del Burgo, C. Osorio, A. Makonda, B. de Irala, J. Sci Rep Article Retention is a key element in HIV prevention programs. In Sub-Saharan Africa most data on retention come from HIV clinical trials or people living with HIV attending HIV treatment and control programs. Data from observational cohorts are less frequent. Retention at 6-/12-month follow-up and its predictors were analyzed in OKAPI prospective cohort. From April 2016 to April 2018, 797 participants aged 15–59 years attending HIV Voluntary Counseling and Testing in Kinshasa were interviewed about HIV-related knowledge and behaviors at baseline and at 6- and 12-month follow-ups. Retention rates were 57% and 27% at 6- and 12-month follow up; 22% of participants attended both visits. Retention at 6-month was significantly associated with 12-month retention. Retention was associated with low economic status, being studying, daily/weekly Internet access, previous HIV tests and aiming to share HIV test with partner. Contrarily, perceiving a good health, living far from an antiretroviral center, daily/weekly alcohol consumption and perceiving frequent HIV information were inversely associated with retention. In conclusion, a high attrition was found among people attending HIV testing participating in a prospective cohort in Kinshasa. Considering the low retention rates and the predictors found in this study, more HIV cohort studies in Kinshasa need to be evaluated to identify local factors and strategies that could improve retention if needed. Nature Publishing Group UK 2021-03-08 /pmc/articles/PMC7970874/ /pubmed/33686218 http://dx.doi.org/10.1038/s41598-021-84839-w Text en © The Author(s) 2021 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Carlos, S.
Burgueño, E.
Ndarabu, A.
Reina, G.
Lopez-del Burgo, C.
Osorio, A.
Makonda, B.
de Irala, J.
Predictors of retention in the prospective HIV prevention OKAPI cohort in Kinshasa
title Predictors of retention in the prospective HIV prevention OKAPI cohort in Kinshasa
title_full Predictors of retention in the prospective HIV prevention OKAPI cohort in Kinshasa
title_fullStr Predictors of retention in the prospective HIV prevention OKAPI cohort in Kinshasa
title_full_unstemmed Predictors of retention in the prospective HIV prevention OKAPI cohort in Kinshasa
title_short Predictors of retention in the prospective HIV prevention OKAPI cohort in Kinshasa
title_sort predictors of retention in the prospective hiv prevention okapi cohort in kinshasa
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7970874/
https://www.ncbi.nlm.nih.gov/pubmed/33686218
http://dx.doi.org/10.1038/s41598-021-84839-w
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