Cargando…
Gene co-expression network analysis in human spinal cord highlights mechanisms underlying amyotrophic lateral sclerosis susceptibility
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease defined by motor neuron (MN) loss. Multiple genetic risk factors have been identified, implicating RNA and protein metabolism and intracellular transport, among other biological mechanisms. To achieve a systems-level understanding of...
Autores principales: | Wang, Jerry C., Ramaswami, Gokul, Geschwind, Daniel H. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7970949/ https://www.ncbi.nlm.nih.gov/pubmed/33707641 http://dx.doi.org/10.1038/s41598-021-85061-4 |
Ejemplares similares
-
Some Spinal Cord Lesions: II. Amyotrophic Lateral Sclerosis
Publicado: (1911) -
Longitudinal evaluation of cerebral and spinal cord damage in Amyotrophic Lateral Sclerosis
por: de Albuquerque, Milena, et al.
Publicado: (2017) -
Alterations in lipid metabolism of spinal cord linked to amyotrophic lateral sclerosis
por: Chaves-Filho, Adriano Britto, et al.
Publicado: (2019) -
Key Disease Mechanisms Linked to Amyotrophic Lateral Sclerosis in Spinal Cord Motor Neurons
por: Bottero, Virginie, et al.
Publicado: (2022) -
Spatial Elucidation of Spinal Cord Lipid- and Metabolite- Regulations in Amyotrophic Lateral Sclerosis
por: Hanrieder, Jörg, et al.
Publicado: (2014)