Cargando…

Prediction of tau accumulation in prodromal Alzheimer’s disease using an ensemble machine learning approach

We developed machine learning (ML) algorithms to predict abnormal tau accumulation among patients with prodromal AD. We recruited 64 patients with prodromal AD using the Alzheimer’s Disease Neuroimaging Initiative (ADNI) dataset. Supervised ML approaches based on the random forest (RF) and a gradien...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kim, Jaeho, Park, Yuhyun, Park, Seongbeom, Jang, Hyemin, Kim, Hee Jin, Na, Duk L., Lee, Hyejoo, Seo, Sang Won
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7970986/ https://www.ncbi.nlm.nih.gov/pubmed/33707488 http://dx.doi.org/10.1038/s41598-021-85165-x

Ejemplares similares

A Dextral Primary Progressive Aphasia Patient with Right Dominant Hypometabolism and Tau Accumulation and Left Dominant Amyloid Accumulation
por: Jang, Young Kyoung, et al.
Publicado: (2016)

Prediction of amyloid β PET positivity using machine learning in patients with suspected cerebral amyloid angiopathy markers
por: Jung, Young Hee, et al.
Publicado: (2020)

Identifying a subtype of Alzheimer’s disease characterised by predominant right focal cortical atrophy
por: Kim, Ko Woon, et al.
Publicado: (2020)

Social Event Memory Test (SEMT): A Video-based Memory Test for Predicting Amyloid Positivity for Alzheimer’s Disease
por: Kim, Ko Woon, et al.
Publicado: (2018)

Clinical outcomes of increased focal amyloid uptake in individuals with subthreshold global amyloid levels
por: Kim, Jaeho, et al.
Publicado: (2023)

Potential Applications of Artificial Intelligence in Clinical Trials for Alzheimer’s Disease
por: Seo, Younghoon, et al.
Publicado: (2022)

The Cortical Neuroanatomy Related to Specific Neuropsychological Deficits in Alzheimer's Continuum
por: Kang, Sung Hoon, et al.
Publicado: (2019)

White Matter Lesions Predominantly Located in Deep White Matter Represent Embolic Etiology Rather Than Small Vessel Disease
por: Jung, Young Hee, et al.
Publicado: (2023)

Cerebrospinal Fluid Biomarkers for the Diagnosis and Classification of Alzheimer's Disease Spectrum
por: Lee, Jongmin, et al.
Publicado: (2020)

Frontal-executive dysfunction affects dementia conversion in patients with amnestic mild cognitive impairment
por: Jung, Young Hee, et al.
Publicado: (2020)

Intracerebroventricular injection of human umbilical cord blood mesenchymal stem cells in patients with Alzheimer’s disease dementia: a phase I clinical trial
por: Kim, Hee Jin, et al.
Publicado: (2021)

Differential effects of risk factors on the cognitive trajectory of early- and late-onset Alzheimer’s disease
por: Kim, Jaeho, et al.
Publicado: (2021)

Cerebrospinal Fluid Biomarkers for the Diagnosis of Prodromal Alzheimer's Disease in Amnestic Mild Cognitive Impairment
por: Park, Jung Eun, et al.
Publicado: (2019)

Memory concerns in the early Alzheimer's disease prodrome: Regional association with tau deposition
por: Swinford, Cecily G., et al.
Publicado: (2018)

Sleep and Tau Pathology in Vietnam War Veterans with Preclinical and Prodromal Alzheimer’s Disease
por: Andrews, Murray, et al.
Publicado: (2021)

Head-to-head comparison of 10 plasma phospho-tau assays in prodromal Alzheimer’s disease
por: Janelidze, Shorena, et al.
Publicado: (2022)

The preclinical amyloid sensitive composite to determine subtle cognitive differences in preclinical Alzheimer’s disease
por: Hahn, Alice, et al.
Publicado: (2020)

Interaction between Alzheimer’s Disease and Cerebral Small Vessel Disease: A Review Focused on Neuroimaging Markers
por: Kim, Si Eun, et al.
Publicado: (2022)

Time Perception in Prodromal Alzheimer's Dementia and in Prodromal Dementia With Lewy Bodies
por: Pai, Ming-Chyi, et al.
Publicado: (2021)

Predicting amyloid positivity in patients with mild cognitive impairment using a radiomics approach
por: Kim, Jun Pyo, et al.
Publicado: (2021)

Distinctive Temporal Trajectories of Alzheimer’s Disease Biomarkers According to Sex and APOE Genotype: Importance of Striatal Amyloid
por: Kim, Jun Pyo, et al.
Publicado: (2022)

Predicting conversion of brain β-amyloid positivity in amyloid-negative individuals
por: Park, Chae Jung, et al.
Publicado: (2022)

Appropriate reference region selection of (18)F-florbetaben and (18)F-flutemetamol beta-amyloid PET expressed in Centiloid
por: Cho, Soo Hyun, et al.
Publicado: (2020)

Comprehensive Visual Rating Scale on Magnetic Resonance Imaging: Application to Prodromal Alzheimer Disease
por: Chung, Jae Kyung, et al.
Publicado: (2021)

Staging and quantification of florbetaben PET images using machine learning: impact of predicted regional cortical tracer uptake and amyloid stage on clinical outcomes
por: Kim, Jun Pyo, et al.
Publicado: (2019)

Machine learning based hierarchical classification of frontotemporal dementia and Alzheimer's disease
por: Kim, Jun Pyo, et al.
Publicado: (2019)

Relationships between educational attainment, hypertension, and amyloid negative subcortical vascular dementia: The brain-battering hypothesis
por: Hwangbo, Song, et al.
Publicado: (2022)

Inflammaging as a prodrome to Alzheimer's disease
por: Giunta, Brian, et al.
Publicado: (2008)

Amyloid imaging in prodromal Alzheimer's disease
por: Ossenkoppele, Rik, et al.
Publicado: (2011)

Distinct Brain Regions in Physiological and Pathological Brain Aging
por: Lee, Jin San, et al.
Publicado: (2019)

Cerebrospinal fluid from Alzheimer’s disease patients as an optimal formulation for therapeutic application of mesenchymal stem cells in Alzheimer’s disease
por: Lee, Jeongmin, et al.
Publicado: (2019)

The effects of imaging markers on clinical trajectory in cerebral amyloid angiopathy: a longitudinal study in a memory clinic
por: Jang, Hyemin, et al.
Publicado: (2023)

Disease progression modeling of Alzheimer’s disease according to education level
por: Kim, Ko Woon, et al.
Publicado: (2020)

A Microfluidic System for Stable and Continuous EEG Monitoring from Multiple Larval Zebrafish
por: Lee, Yuhyun, et al.
Publicado: (2020)

Identifying genetic variants for amyloid β in subcortical vascular cognitive impairment
por: Kim, Hang-Rai, et al.
Publicado: (2023)

Brainstem substructures and cognition in prodromal Alzheimer’s disease
por: Dutt, Shubir, et al.
Publicado: (2021)

Deep learning application for the classification of Alzheimer’s disease using (18)F-flortaucipir (AV-1451) tau positron emission tomography
por: Park, Sang Won, et al.
Publicado: (2023)

Intracerebroventricular Administration of Human Umbilical Cord Blood—Derived Mesenchymal Stem Cells Induces Transient Inflammation in a Transgenic Mouse Model and Patients with Alzheimer’s Disease
por: Myeong, Su Hyeon, et al.
Publicado: (2022)

Neuronal ER-Signalosome Proteins as Early Biomarkers in Prodromal Alzheimer's Disease Independent of Amyloid-β Production and Tau Phosphorylation
por: Mesa-Herrera, Fátima, et al.
Publicado: (2022)

Osteoporosis Pre-Screening Using Ensemble Machine Learning in Postmenopausal Korean Women
por: Kwon, Youngihn, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_3d0l5qcu9vucesravaje191bvt