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No difference for changes in BMD between two different cementless hip stem designs 2 years after THA

This study evaluates how 2 different total hip arthroplasty (THA) stems compares regarding adaptive bone remodelling. The stems are both proximally porous coated, aiming for proximal fixation, but with different dispersal of the coating. They are also differently designed regarding the distal tip of...

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Autores principales: Dyreborg, Karen, Solgaard, Søren, Skettrup, Michael, Petersen, Michael Mørk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7971014/
https://www.ncbi.nlm.nih.gov/pubmed/33723344
http://dx.doi.org/10.1038/s41598-021-85424-x
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author Dyreborg, Karen
Solgaard, Søren
Skettrup, Michael
Petersen, Michael Mørk
author_facet Dyreborg, Karen
Solgaard, Søren
Skettrup, Michael
Petersen, Michael Mørk
author_sort Dyreborg, Karen
collection PubMed
description This study evaluates how 2 different total hip arthroplasty (THA) stems compares regarding adaptive bone remodelling. The stems are both proximally porous coated, aiming for proximal fixation, but with different dispersal of the coating. They are also differently designed regarding the distal tip of the stem. We aimed to investigate if there is a difference in periprosthetic adaptive bone remodelling between two different designs. From February 2016 to September 2017, we randomised 62 patients, 1:1 (mean age = 64 years, Female/Male = 28/34), scheduled for an uncemented THA to receive either an EBM or a BM THA stem. We performed dual-energy x-ray absorptiometry (DEXA) scans within a week after surgery and at 3, 6, 12 and 24 months with measurements of bone mineral density (BMD) in the 7 Gruen zones (region of interest (ROI) 1–7). Additionally, Oxford Hip Score and Harris Hip Score were collected at 6, 12 and 24 months. We found a decrease in BMD between the postoperative and the 24-months values in all ROIs for both stems. The greatest decrease over time was seen for both groups in the ROI1 (BM = − 8.4%, p = 0.044, and EBM = − 6.5%, p = 0.001) and ROI7 (BM = − 7%, p = 0.005, and EBM = − 8.6%, p < 0.0005). We found a tendency in ROI2–4 of a higher degree of bone loss in the EBM group. However, this difference only continued beyond 6 months in ROI4 (24 months: BM = − 1.2% and EBM = − 2.8%, p = 0.001). The stems show similar adaptive bone remodelling and are clinically performing well.
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spelling pubmed-79710142021-03-19 No difference for changes in BMD between two different cementless hip stem designs 2 years after THA Dyreborg, Karen Solgaard, Søren Skettrup, Michael Petersen, Michael Mørk Sci Rep Article This study evaluates how 2 different total hip arthroplasty (THA) stems compares regarding adaptive bone remodelling. The stems are both proximally porous coated, aiming for proximal fixation, but with different dispersal of the coating. They are also differently designed regarding the distal tip of the stem. We aimed to investigate if there is a difference in periprosthetic adaptive bone remodelling between two different designs. From February 2016 to September 2017, we randomised 62 patients, 1:1 (mean age = 64 years, Female/Male = 28/34), scheduled for an uncemented THA to receive either an EBM or a BM THA stem. We performed dual-energy x-ray absorptiometry (DEXA) scans within a week after surgery and at 3, 6, 12 and 24 months with measurements of bone mineral density (BMD) in the 7 Gruen zones (region of interest (ROI) 1–7). Additionally, Oxford Hip Score and Harris Hip Score were collected at 6, 12 and 24 months. We found a decrease in BMD between the postoperative and the 24-months values in all ROIs for both stems. The greatest decrease over time was seen for both groups in the ROI1 (BM = − 8.4%, p = 0.044, and EBM = − 6.5%, p = 0.001) and ROI7 (BM = − 7%, p = 0.005, and EBM = − 8.6%, p < 0.0005). We found a tendency in ROI2–4 of a higher degree of bone loss in the EBM group. However, this difference only continued beyond 6 months in ROI4 (24 months: BM = − 1.2% and EBM = − 2.8%, p = 0.001). The stems show similar adaptive bone remodelling and are clinically performing well. Nature Publishing Group UK 2021-03-15 /pmc/articles/PMC7971014/ /pubmed/33723344 http://dx.doi.org/10.1038/s41598-021-85424-x Text en © The Author(s) 2021 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Dyreborg, Karen
Solgaard, Søren
Skettrup, Michael
Petersen, Michael Mørk
No difference for changes in BMD between two different cementless hip stem designs 2 years after THA
title No difference for changes in BMD between two different cementless hip stem designs 2 years after THA
title_full No difference for changes in BMD between two different cementless hip stem designs 2 years after THA
title_fullStr No difference for changes in BMD between two different cementless hip stem designs 2 years after THA
title_full_unstemmed No difference for changes in BMD between two different cementless hip stem designs 2 years after THA
title_short No difference for changes in BMD between two different cementless hip stem designs 2 years after THA
title_sort no difference for changes in bmd between two different cementless hip stem designs 2 years after tha
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7971014/
https://www.ncbi.nlm.nih.gov/pubmed/33723344
http://dx.doi.org/10.1038/s41598-021-85424-x
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