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Isotope separation of (176)Lu a precursor to (177)Lu medical isotope using broadband lasers
A new photoionization scheme accessible by Rhodamine dye lasers is proposed for the isotope separation of (176)Lu. [Formula: see text] [Formula: see text] Optimum conditions for the laser isotope separation have been theoretically computed and compared with the previously reported work. The enrichme...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Nature Publishing Group UK
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7971058/ https://www.ncbi.nlm.nih.gov/pubmed/33731791 http://dx.doi.org/10.1038/s41598-021-85414-z |
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author | Suryanarayana, M. V. |
author_facet | Suryanarayana, M. V. |
author_sort | Suryanarayana, M. V. |
collection | PubMed |
description | A new photoionization scheme accessible by Rhodamine dye lasers is proposed for the isotope separation of (176)Lu. [Formula: see text] [Formula: see text] Optimum conditions for the laser isotope separation have been theoretically computed and compared with the previously reported work. The enrichment of ~ 63% can be obtained with > 22 mg/h production rate even when broadband lasers with bandwidth of 500 MHz are employed for the two step excitation. The simplified system requirements for the photoionization scheme combined with a high production rate of (176)Lu than previously reported is expected to reduce the global shortage of (176)Lu isotope for medical applications. |
format | Online Article Text |
id | pubmed-7971058 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-79710582021-03-19 Isotope separation of (176)Lu a precursor to (177)Lu medical isotope using broadband lasers Suryanarayana, M. V. Sci Rep Article A new photoionization scheme accessible by Rhodamine dye lasers is proposed for the isotope separation of (176)Lu. [Formula: see text] [Formula: see text] Optimum conditions for the laser isotope separation have been theoretically computed and compared with the previously reported work. The enrichment of ~ 63% can be obtained with > 22 mg/h production rate even when broadband lasers with bandwidth of 500 MHz are employed for the two step excitation. The simplified system requirements for the photoionization scheme combined with a high production rate of (176)Lu than previously reported is expected to reduce the global shortage of (176)Lu isotope for medical applications. Nature Publishing Group UK 2021-03-17 /pmc/articles/PMC7971058/ /pubmed/33731791 http://dx.doi.org/10.1038/s41598-021-85414-z Text en © The Author(s) 2021 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Article Suryanarayana, M. V. Isotope separation of (176)Lu a precursor to (177)Lu medical isotope using broadband lasers |
title | Isotope separation of (176)Lu a precursor to (177)Lu medical isotope using broadband lasers |
title_full | Isotope separation of (176)Lu a precursor to (177)Lu medical isotope using broadband lasers |
title_fullStr | Isotope separation of (176)Lu a precursor to (177)Lu medical isotope using broadband lasers |
title_full_unstemmed | Isotope separation of (176)Lu a precursor to (177)Lu medical isotope using broadband lasers |
title_short | Isotope separation of (176)Lu a precursor to (177)Lu medical isotope using broadband lasers |
title_sort | isotope separation of (176)lu a precursor to (177)lu medical isotope using broadband lasers |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7971058/ https://www.ncbi.nlm.nih.gov/pubmed/33731791 http://dx.doi.org/10.1038/s41598-021-85414-z |
work_keys_str_mv | AT suryanarayanamv isotopeseparationof176luaprecursorto177lumedicalisotopeusingbroadbandlasers |