Single-cell profiling reveals an endothelium-mediated immunomodulatory pathway in the eye choroid

The activity and survival of retinal photoreceptors depend on support functions performed by the retinal pigment epithelium (RPE) and on oxygen and nutrients delivered by blood vessels in the underlying choroid. By combining single-cell and bulk RNA sequencing, we categorized mouse RPE/choroid cell...

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Detalles Bibliográficos
Autores principales: Lehmann, Guillermo L., Hanke-Gogokhia, Christin, Hu, Yang, Bareja, Rohan, Salfati, Zelda, Ginsberg, Michael, Nolan, Daniel J., Mendez-Huergo, Santiago P., Dalotto-Moreno, Tomas, Wojcinski, Alexandre, Ochoa, Francisca, Zeng, Shemin, Cerliani, Juan P., Panagis, Lampros, Zager, Patrick J., Mullins, Robert F., Ogura, Shuntaro, Lutty, Gerard A., Bang, Jakyung, Zippin, Jonathan H., Romano, Carmelo, Rabinovich, Gabriel A., Elemento, Olivier, Joyner, Alexandra L., Rafii, Shahin, Rodriguez-Boulan, Enrique, Benedicto, Ignacio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7971135/
https://www.ncbi.nlm.nih.gov/pubmed/32196081
http://dx.doi.org/10.1084/jem.20190730

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