The role of discoidin domain receptor 2 in the renal dysfunction of alport syndrome mouse model

Alport syndrome (AS) is a hereditary glomerular nephritis caused by mutation in one of the type IV collagen genes α3/α4/α5 that encode the heterotrimer COL4A3/4/5. Failure to form a heterotrimer due to mutation leads to the dysfunction of the glomerular basement membrane, and end-stage renal disease...

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Detalles Bibliográficos
Autores principales: Sannomiya, Yuya, Kaseda, Shota, Kamura, Misato, Yamamoto, Hiroshi, Yamada, Hiroyuki, Inamoto, Masataka, Kuwazuru, Jun, Niino, Saki, Shuto, Tsuyoshi, Suico, Mary Ann, Kai, Hirofumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Laboratory Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7971217/
https://www.ncbi.nlm.nih.gov/pubmed/33706638
http://dx.doi.org/10.1080/0886022X.2021.1896548

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