Functional GLP-1R antibodies identified from a synthetic GPCR-focused library demonstrate potent blood glucose control

G protein-coupled receptors (GPCRs) are a group of seven-transmembrane receptor proteins that have proven to be successful drug targets. Antibodies are becoming an increasingly promising modality to target these receptors due to their unique properties, such as exquisite specificity, long half-life,...

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Detalles Bibliográficos
Autores principales: Liu, Qiang, Garg, Pankaj, Hasdemir, Burcu, Wang, Linya, Tuscano, Emily, Sever, Emily, Keane, Erica, Hernandez, Ana G Lujan, Yuan, Tom Z., Kwan, Eric, Lai, Joyce, Szot, Greg, Paruthiyil, Sreenivasan, Axelrod, Fumiko, K. Sato, Aaron
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7971233/
https://www.ncbi.nlm.nih.gov/pubmed/33706686
http://dx.doi.org/10.1080/19420862.2021.1893425

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