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Crystal structure of human interleukin-2 in complex with TCB2, a new antibody-drug candidate with antitumor activity

Immunotherapy via interleukin-2 (IL-2) mediated activation of anti-tumor immune response is a promising approach for cancer treatment. The multi-potent cytokine, IL-2 has a central role in immune cell activation and homeostasis. Since IL-2 preferentially activates immunosuppressive T regulatory cell...

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Detalles Bibliográficos
Autores principales:	Kim, Jieun, Lee, Jun-Young, Park, Suk-Youl, Lee, You Jeong, Kim, Min-Sung
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2021
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7971329/ https://www.ncbi.nlm.nih.gov/pubmed/33796411 http://dx.doi.org/10.1080/2162402X.2021.1899671

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