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Optic nerve head plasmacytoma as a manifestation of multiple myeloma
Extramedullary disease in multiple myeloma is uncommon and associated with a poorer prognosis. Extramedullary disease involving the orbit is even more unusual, with optic nerve involvement being rare. We describe an optic nerve head plasmacytoma in a 45-year-old female in the setting of systemic rel...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer - Medknow
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7971446/ https://www.ncbi.nlm.nih.gov/pubmed/33767963 http://dx.doi.org/10.4103/tjo.tjo_81_20 |
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author | Sandor, Kaitlin P. Micieli, Jonathan A. Peragallo, Jason H. |
author_facet | Sandor, Kaitlin P. Micieli, Jonathan A. Peragallo, Jason H. |
author_sort | Sandor, Kaitlin P. |
collection | PubMed |
description | Extramedullary disease in multiple myeloma is uncommon and associated with a poorer prognosis. Extramedullary disease involving the orbit is even more unusual, with optic nerve involvement being rare. We describe an optic nerve head plasmacytoma in a 45-year-old female in the setting of systemic relapsed, refractory IgA kappa multiple myeloma. The case highlights the importance of keeping extramedullary disease spread in the differential for vision loss in a patient with a history of multiple myeloma. In addition, it describes an unusual location for presentation of extramedullary disease, the optic nerve head, which has rarely been described. |
format | Online Article Text |
id | pubmed-7971446 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Wolters Kluwer - Medknow |
record_format | MEDLINE/PubMed |
spelling | pubmed-79714462021-03-24 Optic nerve head plasmacytoma as a manifestation of multiple myeloma Sandor, Kaitlin P. Micieli, Jonathan A. Peragallo, Jason H. Taiwan J Ophthalmol Case Report Extramedullary disease in multiple myeloma is uncommon and associated with a poorer prognosis. Extramedullary disease involving the orbit is even more unusual, with optic nerve involvement being rare. We describe an optic nerve head plasmacytoma in a 45-year-old female in the setting of systemic relapsed, refractory IgA kappa multiple myeloma. The case highlights the importance of keeping extramedullary disease spread in the differential for vision loss in a patient with a history of multiple myeloma. In addition, it describes an unusual location for presentation of extramedullary disease, the optic nerve head, which has rarely been described. Wolters Kluwer - Medknow 2021-02-10 /pmc/articles/PMC7971446/ /pubmed/33767963 http://dx.doi.org/10.4103/tjo.tjo_81_20 Text en Copyright: © 2021 Taiwan J Ophthalmol http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. |
spellingShingle | Case Report Sandor, Kaitlin P. Micieli, Jonathan A. Peragallo, Jason H. Optic nerve head plasmacytoma as a manifestation of multiple myeloma |
title | Optic nerve head plasmacytoma as a manifestation of multiple myeloma |
title_full | Optic nerve head plasmacytoma as a manifestation of multiple myeloma |
title_fullStr | Optic nerve head plasmacytoma as a manifestation of multiple myeloma |
title_full_unstemmed | Optic nerve head plasmacytoma as a manifestation of multiple myeloma |
title_short | Optic nerve head plasmacytoma as a manifestation of multiple myeloma |
title_sort | optic nerve head plasmacytoma as a manifestation of multiple myeloma |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7971446/ https://www.ncbi.nlm.nih.gov/pubmed/33767963 http://dx.doi.org/10.4103/tjo.tjo_81_20 |
work_keys_str_mv | AT sandorkaitlinp opticnerveheadplasmacytomaasamanifestationofmultiplemyeloma AT micielijonathana opticnerveheadplasmacytomaasamanifestationofmultiplemyeloma AT peragallojasonh opticnerveheadplasmacytomaasamanifestationofmultiplemyeloma |