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Adenosine A(2A) receptor agonist polydeoxyribonucleotide ameliorates short-term memory impairment by suppressing cerebral ischemia-induced inflammation via MAPK pathway
Cerebral ischemia causes tissue death owing to occlusion of the cerebral blood vessels, and cerebral ischemia activates mitogen-activated protein kinase (MAPK) and induces secretion of pro-inflammatory cytokines. Adenosine A(2A) receptor agonist, polydeoxyribonucleotide (PDRN), suppresses the secret...
Autores principales: | Ko, Il-Gyu, Jin, Jun-Jang, Hwang, Lakkyong, Kim, Sang-Hoon, Kim, Chang-Ju, Jeon, Jung Won, Chung, Jun-Young, Han, Jin Hee |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7971468/ https://www.ncbi.nlm.nih.gov/pubmed/33735236 http://dx.doi.org/10.1371/journal.pone.0248689 |
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