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Anti-CD19 CAR T cells potently redirected to kill solid tumor cells

Successful CAR T cell therapy for the treatment of solid tumors requires exemplary CAR T cell expansion, persistence and fitness, and the ability to target tumor antigens safely. Here we address this constellation of critical attributes for successful cellular therapy by using integrated technologie...

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Detalles Bibliográficos
Autores principales:	Ambrose, Christine, Su, Lihe, Wu, Lan, Dufort, Fay J., Sanford, Thomas, Birt, Alyssa, Hackel, Benjamin J., Hombach, Andreas, Abken, Hinrich, Lobb, Roy R., Rennert, Paul D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7971483/ https://www.ncbi.nlm.nih.gov/pubmed/33735268 http://dx.doi.org/10.1371/journal.pone.0247701

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