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Allergic rhinitis is associated with atmospheric SO(2): Follow-up study of children from elementary schools in Ulsan, Korea

OBJECTIVES: The purpose of this study was to examine the association of allergic rhinitis with air pollutant concentrations using the follow-up data of elementary school children in Ulsan, Korea. METHODS: All students of four elementary schools in Ulsan, South Korea were surveyed at two-year interva...

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Autores principales: Kim, Suk Hwan, Lee, Jiho, Oh, Inbo, Oh, Yeonsuh, Sim, Chang Sun, Bang, Jin-Hee, Park, Jungsun, Kim, Yangho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7971526/
https://www.ncbi.nlm.nih.gov/pubmed/33735252
http://dx.doi.org/10.1371/journal.pone.0248624
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author Kim, Suk Hwan
Lee, Jiho
Oh, Inbo
Oh, Yeonsuh
Sim, Chang Sun
Bang, Jin-Hee
Park, Jungsun
Kim, Yangho
author_facet Kim, Suk Hwan
Lee, Jiho
Oh, Inbo
Oh, Yeonsuh
Sim, Chang Sun
Bang, Jin-Hee
Park, Jungsun
Kim, Yangho
author_sort Kim, Suk Hwan
collection PubMed
description OBJECTIVES: The purpose of this study was to examine the association of allergic rhinitis with air pollutant concentrations using the follow-up data of elementary school children in Ulsan, Korea. METHODS: All students of four elementary schools in Ulsan, South Korea were surveyed at two-year intervals. The survey used data collected five times, over a nine-year period from June 2009 to April 2018. The questionnaire used in the survey was a modified version of the ISAAC (International society of asthma and allergy of children) questionnaire. A skin prick test (SPT) was performed with 24 standard antigens. To estimate the levels of exposure to outdoor air pollution, the concentrations of sulfur dioxide (SO(2)), nitrogen dioxide (NO(2)), ozone (O(3)), carbon monoxide (CO), and particulate matter 10 μm or less in diameter (PM10) were used. As a dependent variable, a history of allergic rhinitis diagnosed by a doctor during the last 1-year was considered. Logistic regression analysis was used to select variables suitable for the statistical model. The selected variables were then used to assess their association with the dependent variable using the generalized estimation equation. RESULTS: Among environmental factors, SO(2) was associated with a high risk and PM10 was associated with a low risk of allergic rhinitis. The risk of allergic rhinitis from living in a house built within the last year was high, and the risk from living in a multi-family house or apartment was higher than that from living in a segregated house. History of allergic diseases in the family was a high-risk factor for allergic rhinitis. There was a relationship between a history of bronchiolitis at less than 2 years of age and a high risk of allergic rhinitis. Boys were at a higher risk than girls. CONCLUSION: From the follow-up data of elementary school students in Ulsan, Korea, the concentration of SO(2), which is an indicator of the degree of industrialization, was related to the prevalence of allergic rhinitis. Among all the risk factors, history of allergic disease in the parents was the most important factor, and the study reconfirmed the results of the previous studies.
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spelling pubmed-79715262021-03-31 Allergic rhinitis is associated with atmospheric SO(2): Follow-up study of children from elementary schools in Ulsan, Korea Kim, Suk Hwan Lee, Jiho Oh, Inbo Oh, Yeonsuh Sim, Chang Sun Bang, Jin-Hee Park, Jungsun Kim, Yangho PLoS One Research Article OBJECTIVES: The purpose of this study was to examine the association of allergic rhinitis with air pollutant concentrations using the follow-up data of elementary school children in Ulsan, Korea. METHODS: All students of four elementary schools in Ulsan, South Korea were surveyed at two-year intervals. The survey used data collected five times, over a nine-year period from June 2009 to April 2018. The questionnaire used in the survey was a modified version of the ISAAC (International society of asthma and allergy of children) questionnaire. A skin prick test (SPT) was performed with 24 standard antigens. To estimate the levels of exposure to outdoor air pollution, the concentrations of sulfur dioxide (SO(2)), nitrogen dioxide (NO(2)), ozone (O(3)), carbon monoxide (CO), and particulate matter 10 μm or less in diameter (PM10) were used. As a dependent variable, a history of allergic rhinitis diagnosed by a doctor during the last 1-year was considered. Logistic regression analysis was used to select variables suitable for the statistical model. The selected variables were then used to assess their association with the dependent variable using the generalized estimation equation. RESULTS: Among environmental factors, SO(2) was associated with a high risk and PM10 was associated with a low risk of allergic rhinitis. The risk of allergic rhinitis from living in a house built within the last year was high, and the risk from living in a multi-family house or apartment was higher than that from living in a segregated house. History of allergic diseases in the family was a high-risk factor for allergic rhinitis. There was a relationship between a history of bronchiolitis at less than 2 years of age and a high risk of allergic rhinitis. Boys were at a higher risk than girls. CONCLUSION: From the follow-up data of elementary school students in Ulsan, Korea, the concentration of SO(2), which is an indicator of the degree of industrialization, was related to the prevalence of allergic rhinitis. Among all the risk factors, history of allergic disease in the parents was the most important factor, and the study reconfirmed the results of the previous studies. Public Library of Science 2021-03-18 /pmc/articles/PMC7971526/ /pubmed/33735252 http://dx.doi.org/10.1371/journal.pone.0248624 Text en © 2021 Kim et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Kim, Suk Hwan
Lee, Jiho
Oh, Inbo
Oh, Yeonsuh
Sim, Chang Sun
Bang, Jin-Hee
Park, Jungsun
Kim, Yangho
Allergic rhinitis is associated with atmospheric SO(2): Follow-up study of children from elementary schools in Ulsan, Korea
title Allergic rhinitis is associated with atmospheric SO(2): Follow-up study of children from elementary schools in Ulsan, Korea
title_full Allergic rhinitis is associated with atmospheric SO(2): Follow-up study of children from elementary schools in Ulsan, Korea
title_fullStr Allergic rhinitis is associated with atmospheric SO(2): Follow-up study of children from elementary schools in Ulsan, Korea
title_full_unstemmed Allergic rhinitis is associated with atmospheric SO(2): Follow-up study of children from elementary schools in Ulsan, Korea
title_short Allergic rhinitis is associated with atmospheric SO(2): Follow-up study of children from elementary schools in Ulsan, Korea
title_sort allergic rhinitis is associated with atmospheric so(2): follow-up study of children from elementary schools in ulsan, korea
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7971526/
https://www.ncbi.nlm.nih.gov/pubmed/33735252
http://dx.doi.org/10.1371/journal.pone.0248624
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