Early Insights into COVID-19 in Persons Living with HIV and Cardiovascular Manifestations

Persons living with HIV-1 (PLHIV) are at increased risk of cardiovascular complications in part due to the persistent inflammatory state despite viral suppression. SARS-CoV-2, the virus causing COVID-19, was declared a pandemic virus in March 2020, and caused over 30 million cases and 900,000 deaths...

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Autores principales: Grant, Jelani K., Vincent, Louis, Ebner, Bertrand, Hurwitz, Barry E., Alcaide, Maria L., Martinez, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7971556/
https://www.ncbi.nlm.nih.gov/pubmed/33748827
http://dx.doi.org/10.33696/aids.2.010
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author Grant, Jelani K.
Vincent, Louis
Ebner, Bertrand
Hurwitz, Barry E.
Alcaide, Maria L.
Martinez, Claudia
author_facet Grant, Jelani K.
Vincent, Louis
Ebner, Bertrand
Hurwitz, Barry E.
Alcaide, Maria L.
Martinez, Claudia
author_sort Grant, Jelani K.
collection PubMed
description Persons living with HIV-1 (PLHIV) are at increased risk of cardiovascular complications in part due to the persistent inflammatory state despite viral suppression. SARS-CoV-2, the virus causing COVID-19, was declared a pandemic virus in March 2020, and caused over 30 million cases and 900,000 deaths worldwide to date. Individuals with COVID-19 are manifesting acute cardiovascular complications because of the inflammatory response associated with SARS-CoV-2 infection. It is not yet known whether having COVID-19 in the context of ongoing HIV-1 infection results in worse cardiovascular complications than in PLHIV who have not had COVID-19 infection. In this review, the potential for exacerbated cardiovascular manifestations in persons coinfected with HIV-1 and COVID-19 is considered.
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spelling pubmed-79715562021-03-18 Early Insights into COVID-19 in Persons Living with HIV and Cardiovascular Manifestations Grant, Jelani K. Vincent, Louis Ebner, Bertrand Hurwitz, Barry E. Alcaide, Maria L. Martinez, Claudia J AIDS HIV Treat Article Persons living with HIV-1 (PLHIV) are at increased risk of cardiovascular complications in part due to the persistent inflammatory state despite viral suppression. SARS-CoV-2, the virus causing COVID-19, was declared a pandemic virus in March 2020, and caused over 30 million cases and 900,000 deaths worldwide to date. Individuals with COVID-19 are manifesting acute cardiovascular complications because of the inflammatory response associated with SARS-CoV-2 infection. It is not yet known whether having COVID-19 in the context of ongoing HIV-1 infection results in worse cardiovascular complications than in PLHIV who have not had COVID-19 infection. In this review, the potential for exacerbated cardiovascular manifestations in persons coinfected with HIV-1 and COVID-19 is considered. 2020 /pmc/articles/PMC7971556/ /pubmed/33748827 http://dx.doi.org/10.33696/aids.2.010 Text en http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Article
Grant, Jelani K.
Vincent, Louis
Ebner, Bertrand
Hurwitz, Barry E.
Alcaide, Maria L.
Martinez, Claudia
Early Insights into COVID-19 in Persons Living with HIV and Cardiovascular Manifestations
title Early Insights into COVID-19 in Persons Living with HIV and Cardiovascular Manifestations
title_full Early Insights into COVID-19 in Persons Living with HIV and Cardiovascular Manifestations
title_fullStr Early Insights into COVID-19 in Persons Living with HIV and Cardiovascular Manifestations
title_full_unstemmed Early Insights into COVID-19 in Persons Living with HIV and Cardiovascular Manifestations
title_short Early Insights into COVID-19 in Persons Living with HIV and Cardiovascular Manifestations
title_sort early insights into covid-19 in persons living with hiv and cardiovascular manifestations
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7971556/
https://www.ncbi.nlm.nih.gov/pubmed/33748827
http://dx.doi.org/10.33696/aids.2.010
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