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Dualmarker: a flexible toolset for exploratory analysis of combinatorial dual biomarkers for clinical efficacy
BACKGROUND: An increasing number of clinical trials require biomarker-driven patient stratification, especially for revolutionary immune checkpoint blockade therapy. Due to the complicated interaction between a tumor and its microenvironment, single biomarkers, such as PDL1 protein level, tumor muta...
Autores principales: | Ma, Xiaopeng, Huang, Ruiqi, Wu, Xikun, Zhang, Pei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7972341/ https://www.ncbi.nlm.nih.gov/pubmed/33731020 http://dx.doi.org/10.1186/s12859-021-04050-6 |
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