Chimeric Antigen receptor-T (CAR-T) cells targeting Epithelial cell adhesion molecule (EpCAM) can inhibit tumor growth in ovarian cancer mouse model

Ovarian cancer (OC) is one of the most lethal solid tumors with poor prognosis. In 2017, two chimeric antigen receptor-T (CAR-T) cell drugs were approved by the U.S. Food and Drug Administration (FDA), and continuously optimized CAR-T cells therapy might be the novel hope for OC patient. EpCAM are k...

Descripción completa

Detalles Bibliográficos
Autores principales: FU, Juan, SHANG, Yuhong, QIAN, Zhang, HOU, Jinping, YAN, Feng, LIU, Guodi, DEHUA, Li, TIAN, Xiaoli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Veterinary Science 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7972873/
https://www.ncbi.nlm.nih.gov/pubmed/33328392
http://dx.doi.org/10.1292/jvms.20-0455

Ejemplares similares

Ejemplares similares