The enhancement of Th1 immune response by anti-PD-L1 antibody in cattle infected with Mycobacterium avium subsp. paratuberculosis

Johne’s disease, caused by Mycobacterium avium subsp. paratuberculosis (MAP), is a chronic enteritis of ruminants. Previous studies have shown that programmed death-ligand 1 (PD-L1) is associated with the disease progression, and PD-L1 blockade activates MAP-specific Th1 responses in vitro. Here, we...

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Detalles Bibliográficos
Autores principales: SAJIKI, Yamato, KONNAI, Satoru, NAGATA, Reiko, KAWAJI, Satoko, NAKAMURA, Hayato, FUJISAWA, Sotaro, OKAGAWA, Tomohiro, MAEKAWA, Naoya, KATO, Yukinari, SUZUKI, Yasuhiko, MURATA, Shiro, MORI, Yasuyuki, OHASHI, Kazuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Veterinary Science 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7972883/
https://www.ncbi.nlm.nih.gov/pubmed/33281144
http://dx.doi.org/10.1292/jvms.20-0590

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