Predicting transcription factor binding sites using DNA shape features based on shared hybrid deep learning architecture

The study of transcriptional regulation is still difficult yet fundamental in molecular biology research. Recent research has shown that the double helix structure of nucleotides plays an important role in improving the accuracy and interpretability of transcription factor binding sites (TFBSs). Alt...

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Detalles Bibliográficos
Autores principales: Wang, Siguo, Zhang, Qinhu, Shen, Zhen, He, Ying, Chen, Zhen-Heng, Li, Jianqiang, Huang, De-Shuang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7972936/
https://www.ncbi.nlm.nih.gov/pubmed/33767912
http://dx.doi.org/10.1016/j.omtn.2021.02.014

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