Doppelgänger dilemma: Leiomyoma versus uveal melanoma

BACKGROUND: Ciliary body tumors can remain undetected and achieve large dimensions. Pigmented ciliary body tumors include: melanoma, leiomyoma and melanocytoma, however correct diagnosis may require tissue diagnosis with immunohistochemical stains. CASE PRESENTATION: Two men presented with identical...

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Detalles Bibliográficos
Autores principales: Tomar, Ankit Singh, Fam, Anthony, Finger, Paul T., Iacob, Codrin E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7973119/
https://www.ncbi.nlm.nih.gov/pubmed/33748534
http://dx.doi.org/10.1016/j.ajoc.2021.101040
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author Tomar, Ankit Singh
Fam, Anthony
Finger, Paul T.
Iacob, Codrin E.
author_facet Tomar, Ankit Singh
Fam, Anthony
Finger, Paul T.
Iacob, Codrin E.
author_sort Tomar, Ankit Singh
collection PubMed
description BACKGROUND: Ciliary body tumors can remain undetected and achieve large dimensions. Pigmented ciliary body tumors include: melanoma, leiomyoma and melanocytoma, however correct diagnosis may require tissue diagnosis with immunohistochemical stains. CASE PRESENTATION: Two men presented with identical ciliochoroidal tumors. Both had darkly pigmented dome-shaped anterior uveal masses, exudative retinal detachments and transillumination shadowing. Ocular PET-CT imaging revealed that both were metabolically active consistent with a diagnosis of cancer. However, immunohistochemical examination revealed one a leiomyoma and the other melanoma. CONCLUSION: Uveal leiomyoma can be an indistinguishable doppelgänger to ciliochoroidal melanoma, where the diagnosis can only be established by immunohistopathology.
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spelling pubmed-79731192021-03-19 Doppelgänger dilemma: Leiomyoma versus uveal melanoma Tomar, Ankit Singh Fam, Anthony Finger, Paul T. Iacob, Codrin E. Am J Ophthalmol Case Rep Case Report BACKGROUND: Ciliary body tumors can remain undetected and achieve large dimensions. Pigmented ciliary body tumors include: melanoma, leiomyoma and melanocytoma, however correct diagnosis may require tissue diagnosis with immunohistochemical stains. CASE PRESENTATION: Two men presented with identical ciliochoroidal tumors. Both had darkly pigmented dome-shaped anterior uveal masses, exudative retinal detachments and transillumination shadowing. Ocular PET-CT imaging revealed that both were metabolically active consistent with a diagnosis of cancer. However, immunohistochemical examination revealed one a leiomyoma and the other melanoma. CONCLUSION: Uveal leiomyoma can be an indistinguishable doppelgänger to ciliochoroidal melanoma, where the diagnosis can only be established by immunohistopathology. Elsevier 2021-03-06 /pmc/articles/PMC7973119/ /pubmed/33748534 http://dx.doi.org/10.1016/j.ajoc.2021.101040 Text en © 2021 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Tomar, Ankit Singh
Fam, Anthony
Finger, Paul T.
Iacob, Codrin E.
Doppelgänger dilemma: Leiomyoma versus uveal melanoma
title Doppelgänger dilemma: Leiomyoma versus uveal melanoma
title_full Doppelgänger dilemma: Leiomyoma versus uveal melanoma
title_fullStr Doppelgänger dilemma: Leiomyoma versus uveal melanoma
title_full_unstemmed Doppelgänger dilemma: Leiomyoma versus uveal melanoma
title_short Doppelgänger dilemma: Leiomyoma versus uveal melanoma
title_sort doppelgänger dilemma: leiomyoma versus uveal melanoma
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7973119/
https://www.ncbi.nlm.nih.gov/pubmed/33748534
http://dx.doi.org/10.1016/j.ajoc.2021.101040
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