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Formulation development of itraconazole PEGylated nano-lipid carriers for pulmonary aspergillosis using hot-melt extrusion technology

Pulmonary delivery is a promising alternative for the oral treatment of pulmonary aspergillosis. This study aimed to develop continuous and scalable itraconazole PEGylated nano-lipid carriers (ITZ-PEG-NLC) for inhalation delivery. The feasibility of preparing NLCs utilizing hot-melt extrusion (HME)...

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Detalles Bibliográficos
Autores principales:	Shadambikar, Gauri, Marathe, Sushrut, Ji, Nan, Almutairi, Mashan, Bandari, Suresh, Zhang, Feng, Chougule, Mahavir, Repka, Michael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7973123/ https://www.ncbi.nlm.nih.gov/pubmed/33748741 http://dx.doi.org/10.1016/j.ijpx.2021.100074

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