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Piezo 1 activation facilitates cholangiocarcinoma metastasis via Hippo/YAP signaling axis

Tumor metastasis is one of the major factors for the high mortality in cholangiocarcinoma (CCA), but its underlying mechanisms are not fully understood. Here, we report that Piezo-type mechanosensitive ion channel component 1 (Piezo 1) is detected to be significantly upregulated in CCA tissues, whic...

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Detalles Bibliográficos
Autores principales: Zhu, Biqiang, Qian, Wei, Han, Chaoqun, Bai, Tao, Hou, Xiaohua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7973248/
https://www.ncbi.nlm.nih.gov/pubmed/33767919
http://dx.doi.org/10.1016/j.omtn.2021.02.026

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