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Genetic activation of α-cell glucokinase in mice causes enhanced glucose-suppression of glucagon secretion during normal and diabetic states

OBJECTIVE: While the molecular events controlling insulin secretion from β-cells have been documented in detail, the exact mechanisms governing glucagon release by α-cells are understood only partially. This is a critical knowledge gap, as the normal suppression of glucagon secretion by elevated glu...

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Detalles Bibliográficos
Autores principales:	Bahl, Varun, Lee May, Catherine, Perez, Alanis, Glaser, Benjamin, Kaestner, Klaus H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7973249/ https://www.ncbi.nlm.nih.gov/pubmed/33610858 http://dx.doi.org/10.1016/j.molmet.2021.101193

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