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Thalidomide affects limb formation and multiple myeloma related genes in human induced pluripotent stem cells and their mesoderm differentiation

Although thalidomide is highly teratogenic, it has been prescribed for treating multiple myeloma and Hansen's disease. However, its mechanism of action is not fully understood. Here, we employed a reverse transcription quantitative PCR array to measure the expression of 84 genes in human induce...

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Detalles Bibliográficos
Autores principales: Shimizu, Maho, Tachikawa, Saoko, Saitoh, Nagatsuki, Nakazono, Kohei, Yu-Jung, Liu, Suga, Mika, Ohnuma, Kiyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7973312/
https://www.ncbi.nlm.nih.gov/pubmed/33763605
http://dx.doi.org/10.1016/j.bbrep.2021.100978