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Thalidomide affects limb formation and multiple myeloma related genes in human induced pluripotent stem cells and their mesoderm differentiation
Although thalidomide is highly teratogenic, it has been prescribed for treating multiple myeloma and Hansen's disease. However, its mechanism of action is not fully understood. Here, we employed a reverse transcription quantitative PCR array to measure the expression of 84 genes in human induce...
Autores principales: | Shimizu, Maho, Tachikawa, Saoko, Saitoh, Nagatsuki, Nakazono, Kohei, Yu-Jung, Liu, Suga, Mika, Ohnuma, Kiyoshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7973312/ https://www.ncbi.nlm.nih.gov/pubmed/33763605 http://dx.doi.org/10.1016/j.bbrep.2021.100978 |
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