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Local administration of porcine immunomodulatory, chemotactic and angiogenic extracellular vesicles using engineered cardiac scaffolds for myocardial infarction
The administration of extracellular vesicles (EV) from mesenchymal stromal cells (MSC) is a promising cell-free nanotherapy for tissue repair after myocardial infarction (MI). However, the optimal EV delivery strategy remains undetermined. Here, we designed a novel MSC-EV delivery, using 3D scaffold...
Autores principales: | Monguió-Tortajada, Marta, Prat-Vidal, Cristina, Moron-Font, Miriam, Clos-Sansalvador, Marta, Calle, Alexandra, Gastelurrutia, Paloma, Cserkoova, Adriana, Morancho, Anna, Ramírez, Miguel Ángel, Rosell, Anna, Bayes-Genis, Antoni, Gálvez-Montón, Carolina, Borràs, Francesc E., Roura, Santiago |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
KeAi Publishing
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7973387/ https://www.ncbi.nlm.nih.gov/pubmed/33778207 http://dx.doi.org/10.1016/j.bioactmat.2021.02.026 |
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