Sparsely methylated mitochondrial cell free DNA released from cardiomyocytes contributes to systemic inflammatory response accompanied by atrial fibrillation

Systemic inflammation is assumed to be the consequence and the cause of atrial fibrillation (AF); however, the underlying mechanism remains unclear. We aimed to evaluate the level of cell-free DNA (cfDNA) in patients with AF and AF mimicking models, and to illuminate its impact on inflammation. Peri...

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Detalles Bibliográficos
Autores principales: Yamazoe, Masahiro, Sasano, Tetsuo, Ihara, Kensuke, Takahashi, Kentaro, Nakamura, Wakana, Takahashi, Naomi, Komuro, Hiroaki, Hamada, Satomi, Furukawa, Tetsushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7973420/
https://www.ncbi.nlm.nih.gov/pubmed/33737532
http://dx.doi.org/10.1038/s41598-021-85204-7

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