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Microsomic and macrosomic body structure in children and adolescents affected by syndromes or diseases associated with neurodysfunction

In Poland the issue of microsomic body structure (micro-SBS) and macrosomic body structure (macro-SBS) has so far been overlooked. Up until now only a small amount of data have been published, most often as an overview of the problem. The current study was designed to investigate the co-occurrence o...

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Autores principales: Perenc, Lidia, Guzik, Agnieszka, Podgórska-Bednarz, Justyna, Drużbicki, Mariusz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7973426/
https://www.ncbi.nlm.nih.gov/pubmed/33737592
http://dx.doi.org/10.1038/s41598-021-85587-7
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author Perenc, Lidia
Guzik, Agnieszka
Podgórska-Bednarz, Justyna
Drużbicki, Mariusz
author_facet Perenc, Lidia
Guzik, Agnieszka
Podgórska-Bednarz, Justyna
Drużbicki, Mariusz
author_sort Perenc, Lidia
collection PubMed
description In Poland the issue of microsomic body structure (micro-SBS) and macrosomic body structure (macro-SBS) has so far been overlooked. Up until now only a small amount of data have been published, most often as an overview of the problem. The current study was designed to investigate the co-occurrence of microsomic/macrosomic body structure (micro/macro-SBS) and congenital nervous system disorders or neurological syndromes with symptoms visible from infancy, based on essential data acquired during admission procedures at a neurological rehabilitation ward for children and adolescents. The study applied a retrospective analysis of data collected during hospitalization of 327 children and adolescents, aged 4–18 years who had been affected since infancy by congenital disorders of the nervous system and/or neurological syndromes associated with a minimum of one neurodysfunction. To identify subjects with microsomic or macrosomic body structure in the group of children and adolescents, the adopted criteria took into account z-score values for body height (z-score Ht), body weight (z-score Wt), head circumference (z-score HC), BMI (z-score BMI) and head circumference index (z-score HCI). The rates of micro/macro-SBS in the study group amounted to 7.3% and 0.6%, respectively. The findings show a more frequent co-occurrence of, as well as statistically significant correlations between, micro/macro-SBS and type of spasticity (cerebral palsy) (p = 0.024) as well as hydrocephalus not treated surgically (p < 0.001). Macro-SBS was found to more frequently co-occur with hemiplegia and hydrocephalus not treated surgically.
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spelling pubmed-79734262021-03-19 Microsomic and macrosomic body structure in children and adolescents affected by syndromes or diseases associated with neurodysfunction Perenc, Lidia Guzik, Agnieszka Podgórska-Bednarz, Justyna Drużbicki, Mariusz Sci Rep Article In Poland the issue of microsomic body structure (micro-SBS) and macrosomic body structure (macro-SBS) has so far been overlooked. Up until now only a small amount of data have been published, most often as an overview of the problem. The current study was designed to investigate the co-occurrence of microsomic/macrosomic body structure (micro/macro-SBS) and congenital nervous system disorders or neurological syndromes with symptoms visible from infancy, based on essential data acquired during admission procedures at a neurological rehabilitation ward for children and adolescents. The study applied a retrospective analysis of data collected during hospitalization of 327 children and adolescents, aged 4–18 years who had been affected since infancy by congenital disorders of the nervous system and/or neurological syndromes associated with a minimum of one neurodysfunction. To identify subjects with microsomic or macrosomic body structure in the group of children and adolescents, the adopted criteria took into account z-score values for body height (z-score Ht), body weight (z-score Wt), head circumference (z-score HC), BMI (z-score BMI) and head circumference index (z-score HCI). The rates of micro/macro-SBS in the study group amounted to 7.3% and 0.6%, respectively. The findings show a more frequent co-occurrence of, as well as statistically significant correlations between, micro/macro-SBS and type of spasticity (cerebral palsy) (p = 0.024) as well as hydrocephalus not treated surgically (p < 0.001). Macro-SBS was found to more frequently co-occur with hemiplegia and hydrocephalus not treated surgically. Nature Publishing Group UK 2021-03-18 /pmc/articles/PMC7973426/ /pubmed/33737592 http://dx.doi.org/10.1038/s41598-021-85587-7 Text en © The Author(s) 2021 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Perenc, Lidia
Guzik, Agnieszka
Podgórska-Bednarz, Justyna
Drużbicki, Mariusz
Microsomic and macrosomic body structure in children and adolescents affected by syndromes or diseases associated with neurodysfunction
title Microsomic and macrosomic body structure in children and adolescents affected by syndromes or diseases associated with neurodysfunction
title_full Microsomic and macrosomic body structure in children and adolescents affected by syndromes or diseases associated with neurodysfunction
title_fullStr Microsomic and macrosomic body structure in children and adolescents affected by syndromes or diseases associated with neurodysfunction
title_full_unstemmed Microsomic and macrosomic body structure in children and adolescents affected by syndromes or diseases associated with neurodysfunction
title_short Microsomic and macrosomic body structure in children and adolescents affected by syndromes or diseases associated with neurodysfunction
title_sort microsomic and macrosomic body structure in children and adolescents affected by syndromes or diseases associated with neurodysfunction
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7973426/
https://www.ncbi.nlm.nih.gov/pubmed/33737592
http://dx.doi.org/10.1038/s41598-021-85587-7
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