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A multi-institutional survey of the quality of life after treatment for uterine cervical cancer: a comparison between radical radiotherapy and surgery in Japan

This study aimed to research the post-treatment quality of life (QOL) between radiotherapy (RT)- and operation (OP)-treated early cervical cancer survivors, using separate questionnaires for physicians and patients. We administered an observational questionnaire to patients aged 20–70 years old with...

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Autores principales: Kaneyasu, Yuko, Fujiwara, Hisaya, Nishimura, Tetsuo, Sakurai, Hideyuki, Kazumoto, Tomoko, Ikushima, Hitoshi, Uno, Takashi, Tokumaru, Sunao, Harima, Yoko, Gomi, Hiromichi, Toita, Takafumi, Kita, Midori, Noda, Shin-ei, Takahashi, Takeo, Kato, Shingo, Ohkawa, Ayako, Tozawa-Ono, Akiko, Ushijima, Hiroki, Hasumi, Yoko, Hirashima, Yasuyuki, Niibe, Yuzuru, Nakagawa, Tomio, Akita, Tomoyuki, Tanaka, Junko, Ohno, Tatsuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7973450/
https://www.ncbi.nlm.nih.gov/pubmed/33415337
http://dx.doi.org/10.1093/jrr/rraa107
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author Kaneyasu, Yuko
Fujiwara, Hisaya
Nishimura, Tetsuo
Sakurai, Hideyuki
Kazumoto, Tomoko
Ikushima, Hitoshi
Uno, Takashi
Tokumaru, Sunao
Harima, Yoko
Gomi, Hiromichi
Toita, Takafumi
Kita, Midori
Noda, Shin-ei
Takahashi, Takeo
Kato, Shingo
Ohkawa, Ayako
Tozawa-Ono, Akiko
Ushijima, Hiroki
Hasumi, Yoko
Hirashima, Yasuyuki
Niibe, Yuzuru
Nakagawa, Tomio
Akita, Tomoyuki
Tanaka, Junko
Ohno, Tatsuya
author_facet Kaneyasu, Yuko
Fujiwara, Hisaya
Nishimura, Tetsuo
Sakurai, Hideyuki
Kazumoto, Tomoko
Ikushima, Hitoshi
Uno, Takashi
Tokumaru, Sunao
Harima, Yoko
Gomi, Hiromichi
Toita, Takafumi
Kita, Midori
Noda, Shin-ei
Takahashi, Takeo
Kato, Shingo
Ohkawa, Ayako
Tozawa-Ono, Akiko
Ushijima, Hiroki
Hasumi, Yoko
Hirashima, Yasuyuki
Niibe, Yuzuru
Nakagawa, Tomio
Akita, Tomoyuki
Tanaka, Junko
Ohno, Tatsuya
author_sort Kaneyasu, Yuko
collection PubMed
description This study aimed to research the post-treatment quality of life (QOL) between radiotherapy (RT)- and operation (OP)-treated early cervical cancer survivors, using separate questionnaires for physicians and patients. We administered an observational questionnaire to patients aged 20–70 years old with Stages IB1–IIB cervical cancer who had undergone RT or OP and without recurrence as outpatients for ≥6 months after treatment. We divided 100 registered patients equally into two treatment groups (n = 50 each). The average age was 53 and 44 years in the RT and OP groups, respectively. The RT group included 34 and 66% Stage I and II patients, respectively, whereas the OP group included 66 and 34% Stage I and II patients, respectively. The OP group included 58% of patients with postoperative RT. Combination chemotherapy was performed in 84 and 48% of patients in the RT and OP groups, respectively. On the physicians’ questionnaire, we observed significant differences in bone marrow suppression (RT) and leg edema (OP). On the patients’ questionnaire, significantly more patients had dysuria and leg edema in the OP group than in the RT group, and severe (Score 4–5) leg edema was significantly higher in the post-operative RT group than in the OP only group. The frequency of sexual intercourse decreased after treatment in both groups. On the patients’ questionnaire, there were no significant differences between the two groups regarding sexual activity. These findings are useful to patients and physicians for shared decision-making in treatment choices. The guidance of everyday life and health information including sexual life after treatment is important.
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spelling pubmed-79734502021-03-23 A multi-institutional survey of the quality of life after treatment for uterine cervical cancer: a comparison between radical radiotherapy and surgery in Japan Kaneyasu, Yuko Fujiwara, Hisaya Nishimura, Tetsuo Sakurai, Hideyuki Kazumoto, Tomoko Ikushima, Hitoshi Uno, Takashi Tokumaru, Sunao Harima, Yoko Gomi, Hiromichi Toita, Takafumi Kita, Midori Noda, Shin-ei Takahashi, Takeo Kato, Shingo Ohkawa, Ayako Tozawa-Ono, Akiko Ushijima, Hiroki Hasumi, Yoko Hirashima, Yasuyuki Niibe, Yuzuru Nakagawa, Tomio Akita, Tomoyuki Tanaka, Junko Ohno, Tatsuya J Radiat Res Oncology/Medicine This study aimed to research the post-treatment quality of life (QOL) between radiotherapy (RT)- and operation (OP)-treated early cervical cancer survivors, using separate questionnaires for physicians and patients. We administered an observational questionnaire to patients aged 20–70 years old with Stages IB1–IIB cervical cancer who had undergone RT or OP and without recurrence as outpatients for ≥6 months after treatment. We divided 100 registered patients equally into two treatment groups (n = 50 each). The average age was 53 and 44 years in the RT and OP groups, respectively. The RT group included 34 and 66% Stage I and II patients, respectively, whereas the OP group included 66 and 34% Stage I and II patients, respectively. The OP group included 58% of patients with postoperative RT. Combination chemotherapy was performed in 84 and 48% of patients in the RT and OP groups, respectively. On the physicians’ questionnaire, we observed significant differences in bone marrow suppression (RT) and leg edema (OP). On the patients’ questionnaire, significantly more patients had dysuria and leg edema in the OP group than in the RT group, and severe (Score 4–5) leg edema was significantly higher in the post-operative RT group than in the OP only group. The frequency of sexual intercourse decreased after treatment in both groups. On the patients’ questionnaire, there were no significant differences between the two groups regarding sexual activity. These findings are useful to patients and physicians for shared decision-making in treatment choices. The guidance of everyday life and health information including sexual life after treatment is important. Oxford University Press 2021-01-07 /pmc/articles/PMC7973450/ /pubmed/33415337 http://dx.doi.org/10.1093/jrr/rraa107 Text en © The Author(s) 2021. Published by Oxford University Press on behalf of The Japanese Radiation Research Society and Japanese Society for Radiation Oncology. http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Oncology/Medicine
Kaneyasu, Yuko
Fujiwara, Hisaya
Nishimura, Tetsuo
Sakurai, Hideyuki
Kazumoto, Tomoko
Ikushima, Hitoshi
Uno, Takashi
Tokumaru, Sunao
Harima, Yoko
Gomi, Hiromichi
Toita, Takafumi
Kita, Midori
Noda, Shin-ei
Takahashi, Takeo
Kato, Shingo
Ohkawa, Ayako
Tozawa-Ono, Akiko
Ushijima, Hiroki
Hasumi, Yoko
Hirashima, Yasuyuki
Niibe, Yuzuru
Nakagawa, Tomio
Akita, Tomoyuki
Tanaka, Junko
Ohno, Tatsuya
A multi-institutional survey of the quality of life after treatment for uterine cervical cancer: a comparison between radical radiotherapy and surgery in Japan
title A multi-institutional survey of the quality of life after treatment for uterine cervical cancer: a comparison between radical radiotherapy and surgery in Japan
title_full A multi-institutional survey of the quality of life after treatment for uterine cervical cancer: a comparison between radical radiotherapy and surgery in Japan
title_fullStr A multi-institutional survey of the quality of life after treatment for uterine cervical cancer: a comparison between radical radiotherapy and surgery in Japan
title_full_unstemmed A multi-institutional survey of the quality of life after treatment for uterine cervical cancer: a comparison between radical radiotherapy and surgery in Japan
title_short A multi-institutional survey of the quality of life after treatment for uterine cervical cancer: a comparison between radical radiotherapy and surgery in Japan
title_sort multi-institutional survey of the quality of life after treatment for uterine cervical cancer: a comparison between radical radiotherapy and surgery in japan
topic Oncology/Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7973450/
https://www.ncbi.nlm.nih.gov/pubmed/33415337
http://dx.doi.org/10.1093/jrr/rraa107
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