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Evaluation of UBE3A antibodies in mice and human cerebral organoids
UBE3A is an E3 ubiquitin ligase encoded by the neurally imprinted UBE3A gene. The abundance and subcellular distribution of UBE3A has been the topic of many previous studies as its dosage and localization has been linked to neurodevelopmental disorders including Autism, Dup15q syndrome, and Angelman...
Autores principales: | Sen, Dilara, Drobna, Zuzana, Keung, Albert J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7973473/ https://www.ncbi.nlm.nih.gov/pubmed/33737669 http://dx.doi.org/10.1038/s41598-021-85923-x |
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