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Evaluation of UBE3A antibodies in mice and human cerebral organoids

UBE3A is an E3 ubiquitin ligase encoded by the neurally imprinted UBE3A gene. The abundance and subcellular distribution of UBE3A has been the topic of many previous studies as its dosage and localization has been linked to neurodevelopmental disorders including Autism, Dup15q syndrome, and Angelman...

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Detalles Bibliográficos
Autores principales: Sen, Dilara, Drobna, Zuzana, Keung, Albert J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7973473/
https://www.ncbi.nlm.nih.gov/pubmed/33737669
http://dx.doi.org/10.1038/s41598-021-85923-x

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