The effects of myelin on macrophage activation are phenotypic specific via cPLA(2) in the context of spinal cord injury inflammation

Spinal cord injury (SCI) produces chronic, pro-inflammatory macrophage activation that impairs recovery. The mechanisms driving this chronic inflammation are not well understood. Here, we detail the effects of myelin debris on macrophage physiology and demonstrate a novel, activation state-dependent...

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Detalles Bibliográficos
Autores principales: Kopper, Timothy J., Zhang, Bei, Bailey, William M., Bethel, Kara E., Gensel, John C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7973514/
https://www.ncbi.nlm.nih.gov/pubmed/33737707
http://dx.doi.org/10.1038/s41598-021-85863-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7973514/
https://www.ncbi.nlm.nih.gov/pubmed/33737707
http://dx.doi.org/10.1038/s41598-021-85863-6

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