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Destruction of Staphylococcus aureus biofilms by combining an antibiotic with subtilisin A or calcium gluconate
In S. aureus biofilms, bacteria are embedded in a matrix of extracellular polymeric substances (EPS) and are highly tolerant to antimicrobial drugs. We thus sought to identify non-antibiotic substances with broad-spectrum activity able to destroy the EPS matrix and enhance the effect of antibiotics...
Autores principales: | Liu, JingJing, Madec, Jean-Yves, Bousquet-Mélou, Alain, Haenni, Marisa, Ferran, Aude A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7973569/ https://www.ncbi.nlm.nih.gov/pubmed/33737602 http://dx.doi.org/10.1038/s41598-021-85722-4 |
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