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Epidemiological analysis of asymptomatic SARS-CoV-2 transmission in the community: an individual-based model
We established an individual-based computer model to simulate the occurrence, infection, discovery, quarantine, and quarantine release (recovery) of asymptomatic SARS-CoV-2 infected individuals or patients within the community. The model was used to explore the effects of control measures, such as a...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7973571/ https://www.ncbi.nlm.nih.gov/pubmed/33737558 http://dx.doi.org/10.1038/s41598-021-84893-4 |
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author | Guo, Zuiyuan Xiao, Dan |
author_facet | Guo, Zuiyuan Xiao, Dan |
author_sort | Guo, Zuiyuan |
collection | PubMed |
description | We established an individual-based computer model to simulate the occurrence, infection, discovery, quarantine, and quarantine release (recovery) of asymptomatic SARS-CoV-2 infected individuals or patients within the community. The model was used to explore the effects of control measures, such as active tracing, laboratory testing, active treatment, and home quarantine on the epidemic. Considering the condition that R(0) = 1.2, when a case of an imported asymptomatic infected individual (AII) was reported in the community, the implementation of control measures reduced the number of AIIs and patients by 62.2% and 62.4%, respectively. The number of undetected AIIs and patients peaked at 302 days of the epidemic, reaching 53 and 20 individuals, respectively. The implementation of sustained active tracing, laboratory testing, active treatment, and home quarantine can significantly reduce the probability of disease outbreaks and block the spread of the COVID-19 epidemic caused by AIIs in the community. |
format | Online Article Text |
id | pubmed-7973571 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-79735712021-03-19 Epidemiological analysis of asymptomatic SARS-CoV-2 transmission in the community: an individual-based model Guo, Zuiyuan Xiao, Dan Sci Rep Article We established an individual-based computer model to simulate the occurrence, infection, discovery, quarantine, and quarantine release (recovery) of asymptomatic SARS-CoV-2 infected individuals or patients within the community. The model was used to explore the effects of control measures, such as active tracing, laboratory testing, active treatment, and home quarantine on the epidemic. Considering the condition that R(0) = 1.2, when a case of an imported asymptomatic infected individual (AII) was reported in the community, the implementation of control measures reduced the number of AIIs and patients by 62.2% and 62.4%, respectively. The number of undetected AIIs and patients peaked at 302 days of the epidemic, reaching 53 and 20 individuals, respectively. The implementation of sustained active tracing, laboratory testing, active treatment, and home quarantine can significantly reduce the probability of disease outbreaks and block the spread of the COVID-19 epidemic caused by AIIs in the community. Nature Publishing Group UK 2021-03-18 /pmc/articles/PMC7973571/ /pubmed/33737558 http://dx.doi.org/10.1038/s41598-021-84893-4 Text en © The Author(s) 2021 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Article Guo, Zuiyuan Xiao, Dan Epidemiological analysis of asymptomatic SARS-CoV-2 transmission in the community: an individual-based model |
title | Epidemiological analysis of asymptomatic SARS-CoV-2 transmission in the community: an individual-based model |
title_full | Epidemiological analysis of asymptomatic SARS-CoV-2 transmission in the community: an individual-based model |
title_fullStr | Epidemiological analysis of asymptomatic SARS-CoV-2 transmission in the community: an individual-based model |
title_full_unstemmed | Epidemiological analysis of asymptomatic SARS-CoV-2 transmission in the community: an individual-based model |
title_short | Epidemiological analysis of asymptomatic SARS-CoV-2 transmission in the community: an individual-based model |
title_sort | epidemiological analysis of asymptomatic sars-cov-2 transmission in the community: an individual-based model |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7973571/ https://www.ncbi.nlm.nih.gov/pubmed/33737558 http://dx.doi.org/10.1038/s41598-021-84893-4 |
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