Performance of preclinical models in predicting drug-induced liver injury in humans: a systematic review

Drug-induced liver injury (DILI) causes one in three market withdrawals due to adverse drug reactions, causing preventable human suffering and massive financial loss. We applied evidence-based methods to investigate the role of preclinical studies in predicting human DILI using two anti-diabetic dru...

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Detalles Bibliográficos
Autores principales: Dirven, Hubert, Vist, Gunn E., Bandhakavi, Sricharan, Mehta, Jyotsna, Fitch, Seneca E., Pound, Pandora, Ram, Rebecca, Kincaid, Breanne, Leenaars, Cathalijn H. C., Chen, Minjun, Wright, Robert A., Tsaioun, Katya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7973584/
https://www.ncbi.nlm.nih.gov/pubmed/33737635
http://dx.doi.org/10.1038/s41598-021-85708-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7973584/
https://www.ncbi.nlm.nih.gov/pubmed/33737635
http://dx.doi.org/10.1038/s41598-021-85708-2

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