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Regulation of cardiomyocyte DNA damage and cell death by the type 2A protein phosphatase regulatory protein alpha4

The type 2A protein phosphatase regulatory protein alpha4 (α4) constitutes an anti-apoptotic protein in non-cardiac tissue, however it’s anti-apoptotic properties in the heart are poorly defined. To this end, we knocked down α4 protein expression (α4 KD) using siRNA in cultured H9c2 cardiomyocytes a...

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Detalles Bibliográficos
Autores principales: Cowan, Jonathan, Longman, Michael R., Snabaitis, Andrew K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7973735/
https://www.ncbi.nlm.nih.gov/pubmed/33737606
http://dx.doi.org/10.1038/s41598-021-85616-5