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Time spent outdoors in childhood is associated with reduced risk of myopia as an adult

Myopia (near-sightedness) is an important public health issue. Spending more time outdoors can prevent myopia but the long-term association between this exposure and myopia has not been well characterised. We investigated the relationship between time spent outdoors in childhood, adolescence and you...

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Autores principales: Lingham, Gareth, Yazar, Seyhan, Lucas, Robyn M., Milne, Elizabeth, Hewitt, Alex W., Hammond, Christopher J., MacGregor, Stuart, Rose, Kathryn A., Chen, Fred K., He, Mingguang, Guggenheim, Jeremy A., Clarke, Michael W., Saw, Seang-Mei, Williams, Cathy, Coroneo, Minas T., Straker, Leon, Mackey, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7973740/
https://www.ncbi.nlm.nih.gov/pubmed/33737652
http://dx.doi.org/10.1038/s41598-021-85825-y
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author Lingham, Gareth
Yazar, Seyhan
Lucas, Robyn M.
Milne, Elizabeth
Hewitt, Alex W.
Hammond, Christopher J.
MacGregor, Stuart
Rose, Kathryn A.
Chen, Fred K.
He, Mingguang
Guggenheim, Jeremy A.
Clarke, Michael W.
Saw, Seang-Mei
Williams, Cathy
Coroneo, Minas T.
Straker, Leon
Mackey, David A.
author_facet Lingham, Gareth
Yazar, Seyhan
Lucas, Robyn M.
Milne, Elizabeth
Hewitt, Alex W.
Hammond, Christopher J.
MacGregor, Stuart
Rose, Kathryn A.
Chen, Fred K.
He, Mingguang
Guggenheim, Jeremy A.
Clarke, Michael W.
Saw, Seang-Mei
Williams, Cathy
Coroneo, Minas T.
Straker, Leon
Mackey, David A.
author_sort Lingham, Gareth
collection PubMed
description Myopia (near-sightedness) is an important public health issue. Spending more time outdoors can prevent myopia but the long-term association between this exposure and myopia has not been well characterised. We investigated the relationship between time spent outdoors in childhood, adolescence and young adulthood and risk of myopia in young adulthood. The Kidskin Young Adult Myopia Study (KYAMS) was a follow-up of the Kidskin Study, a sun exposure-intervention study of 1776 children aged 6–12 years. Myopia status was assessed in 303 (17.6%) KYAMS participants (aged 25–30 years) and several subjective and objective measures of time spent outdoors were collected in childhood (8–12 years) and adulthood. Index measures of total, childhood and recent time spent outdoors were developed using confirmatory factor analysis. Logistic regression was used to assess the association between a 0.1-unit change in the time outdoor indices and risk of myopia after adjusting for sex, education, outdoor occupation, parental myopia, parental education, ancestry and Kidskin Study intervention group. Spending more time outdoors during childhood was associated with reduced risk of myopia in young adulthood (multivariable odds ratio [OR] 0.82, 95% confidence interval [CI] 0.69, 0.98). Spending more time outdoors in later adolescence and young adulthood was associated with reduced risk of late-onset myopia (≥ 15 years of age, multivariable OR 0.79, 95% CI 0.64, 0.98). Spending more time outdoors in both childhood and adolescence was associated with less myopia in young adulthood.
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spelling pubmed-79737402021-03-19 Time spent outdoors in childhood is associated with reduced risk of myopia as an adult Lingham, Gareth Yazar, Seyhan Lucas, Robyn M. Milne, Elizabeth Hewitt, Alex W. Hammond, Christopher J. MacGregor, Stuart Rose, Kathryn A. Chen, Fred K. He, Mingguang Guggenheim, Jeremy A. Clarke, Michael W. Saw, Seang-Mei Williams, Cathy Coroneo, Minas T. Straker, Leon Mackey, David A. Sci Rep Article Myopia (near-sightedness) is an important public health issue. Spending more time outdoors can prevent myopia but the long-term association between this exposure and myopia has not been well characterised. We investigated the relationship between time spent outdoors in childhood, adolescence and young adulthood and risk of myopia in young adulthood. The Kidskin Young Adult Myopia Study (KYAMS) was a follow-up of the Kidskin Study, a sun exposure-intervention study of 1776 children aged 6–12 years. Myopia status was assessed in 303 (17.6%) KYAMS participants (aged 25–30 years) and several subjective and objective measures of time spent outdoors were collected in childhood (8–12 years) and adulthood. Index measures of total, childhood and recent time spent outdoors were developed using confirmatory factor analysis. Logistic regression was used to assess the association between a 0.1-unit change in the time outdoor indices and risk of myopia after adjusting for sex, education, outdoor occupation, parental myopia, parental education, ancestry and Kidskin Study intervention group. Spending more time outdoors during childhood was associated with reduced risk of myopia in young adulthood (multivariable odds ratio [OR] 0.82, 95% confidence interval [CI] 0.69, 0.98). Spending more time outdoors in later adolescence and young adulthood was associated with reduced risk of late-onset myopia (≥ 15 years of age, multivariable OR 0.79, 95% CI 0.64, 0.98). Spending more time outdoors in both childhood and adolescence was associated with less myopia in young adulthood. Nature Publishing Group UK 2021-03-18 /pmc/articles/PMC7973740/ /pubmed/33737652 http://dx.doi.org/10.1038/s41598-021-85825-y Text en © The Author(s) 2021 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Lingham, Gareth
Yazar, Seyhan
Lucas, Robyn M.
Milne, Elizabeth
Hewitt, Alex W.
Hammond, Christopher J.
MacGregor, Stuart
Rose, Kathryn A.
Chen, Fred K.
He, Mingguang
Guggenheim, Jeremy A.
Clarke, Michael W.
Saw, Seang-Mei
Williams, Cathy
Coroneo, Minas T.
Straker, Leon
Mackey, David A.
Time spent outdoors in childhood is associated with reduced risk of myopia as an adult
title Time spent outdoors in childhood is associated with reduced risk of myopia as an adult
title_full Time spent outdoors in childhood is associated with reduced risk of myopia as an adult
title_fullStr Time spent outdoors in childhood is associated with reduced risk of myopia as an adult
title_full_unstemmed Time spent outdoors in childhood is associated with reduced risk of myopia as an adult
title_short Time spent outdoors in childhood is associated with reduced risk of myopia as an adult
title_sort time spent outdoors in childhood is associated with reduced risk of myopia as an adult
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7973740/
https://www.ncbi.nlm.nih.gov/pubmed/33737652
http://dx.doi.org/10.1038/s41598-021-85825-y
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