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Death agonist antibody against TRAILR2/DR5/TNFRSF10B enhances birinapant anti-tumor activity in HPV-positive head and neck squamous cell carcinomas
Head and neck squamous cell carcinomas (HNSCC) induced by human papillomavirus (HPV) have increased recently in the US. However, the distinct alterations of molecules involved in the death pathways and drug effects targeting inhibitor of apoptosis proteins (IAPs) have not been extensively characteri...
Autores principales: | An, Yi, Jeon, Jun, Sun, Lillian, Derakhshan, Adeeb, Chen, Jianhong, Carlson, Sophie, Cheng, Hui, Silvin, Christopher, Yang, Xinping, Van Waes, Carter, Chen, Zhong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7973748/ https://www.ncbi.nlm.nih.gov/pubmed/33737574 http://dx.doi.org/10.1038/s41598-021-85589-5 |
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