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Heparan sulfate is essential for thymus growth

Thymus organogenesis and T cell development are coordinated by various soluble and cell-bound molecules. Heparan sulfate (HS) proteoglycans can interact with and immobilize many soluble mediators, creating fields or gradients of secreted ligands. While the role of HS in the development of many organ...

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Detalles Bibliográficos
Autores principales: Hsu, Hsuan-Po, Chen, Yun-Tzu, Chen, Yu-Ying, Lin, Chih-Yu, Chen, Po-Yu, Liao, Shio-Yi, Lim, Ciara Christianne Y., Yamaguchi, Yu, Hsu, Chia-Lin, Dzhagalov, Ivan L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7974028/
https://www.ncbi.nlm.nih.gov/pubmed/33600795
http://dx.doi.org/10.1016/j.jbc.2021.100419