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Backbone assignment of E. coli NfsB and the effects of addition of the cofactor analogue nicotinic acid
E. coli nitroreductase NfsB (also called NfnB) has been studied extensively, largely due to its potential for cancer gene therapy. A homodimeric flavoprotein of 216 residues, it catalyses the reduction of nitroaromatics to cytotoxic hydroxylamines by NADH and NADPH and also the reduction of quinones...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Springer Netherlands
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7974150/ https://www.ncbi.nlm.nih.gov/pubmed/33423170 http://dx.doi.org/10.1007/s12104-020-09997-w |