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Cytokine secretion and pyroptosis of cholesteatoma keratinocytes mediated by AIM2 inflammasomes in response to cytoplasmic DNA
Cholesteatoma constitutes an acquired benign epidermal non-permanent bone lesion that is locally destructive and patients often relapse. Inflammasomes, which mediate the maturation and production of IL-18 and IL-1β, resulting in pyroptosis, have been documented to serve a core function in multiple i...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
D.A. Spandidos
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7974272/ https://www.ncbi.nlm.nih.gov/pubmed/33760111 http://dx.doi.org/10.3892/mmr.2021.11983 |